| molecular and serologic analysis in the transmission of the gb hepatitis agents. | two flavivirus-like genomes have recently been cloned from infectious tamarin (saguinus labiatus) serum, derived from the human viral hepatitis gb strain, which is known to induce hepatitis in tamarins. in order to study the natural history of gb infections, further transmission studies were carried out in tamarins. reverse-transcription-polymerase chain reaction and enzyme-linked immunosorbant assays were developed for the detection of rna and antibodies associated with the two agents, gb virus ... | 1995 | 7623012 |
| species-specific variants of gb virus a in captive monkeys . | sequences from the putative 5' nontranslated region of gb virus a were isolated from mystax, owl monkeys, and tamarins. though sequences of isolates from each animal species are virtually identical at the nucleotide level (95%), isolates from different species are dramatically different (52 to 79% identical) and genetically cluster on this basis. | 1996 | 8971037 |
| identification of gbv-d, a novel gb-like flavivirus from old world frugivorous bats (pteropus giganteus) in bangladesh. | bats are reservoirs for a wide range of zoonotic agents including lyssa-, henipah-, sars-like corona-, marburg-, ebola-, and astroviruses. in an effort to survey for the presence of other infectious agents, known and unknown, we screened sera from 16 pteropus giganteus bats from faridpur, bangladesh, using high-throughput pyrosequencing. sequence analyses indicated the presence of a previously undescribed virus that has approximately 50% identity at the amino acid level to gb virus a and c (gbv- ... | 2010 | 20617167 |
| discovery of a novel simian pegivirus in common marmosets (callithrix jacchus) with lymphocytic enterocolitis. | from 2010 to 2015, 73 common marmosets (callithrix jacchus) housed at the wisconsin national primate research center (wnprc) were diagnosed postmortem with lymphocytic enterocolitis. we used unbiased deep-sequencing to screen the blood of deceased enterocolitis-positive marmosets for viruses. in five out of eight common marmosets with lymphocytic enterocolitis, we discovered a novel pegivirus not present in ten matched, clinically normal controls. the novel virus, which we named southwest bike t ... | 2020 | 33007921 |
| genetic variability of porcine pegivirus in pigs from europe and china and insights into tissue tropism. | pegiviruses belong to the family flaviviridae and have been found in humans and other mammalian species. to date eleven different pegivirus species (pegivirus a-k) have been described. however, little is known about the tissue tropism and replication of pegiviruses. in 2016, a so far unknown porcine pegivirus (ppgv, pegivirus k) was described and persistent infection in the host, similar to human pegivirus, was reported. in this study, qrt-pcr, phylogenetic analyses and fluorescence in situ hybr ... | 2019 | 31160748 |
| a highly divergent hepacivirus-like flavivirus in domestic ducks. | using random amplification and reverse transcription-pcr, a novel rna virus was detected in sera of domestic ducks. the full genome of the virus was determined for three strains, identifying the first hepacivirus-like flavivirus in birds. the virus, that we tentatively named duck hepacivirus-like virus (duhv), possesses several unique molecular features, such as possession of the largest hepacivirus-like polyprotein gene and a pegivirus a-like internal ribosome entry site. sequence comparisons a ... | 2019 | 31282853 |