| size-polymorphism of mini-exon gene-bearing chromosomes among natural populations of leishmania, subgenus viannia. | in order to explore genomic plasticity at the level of the mini-exon gene-bearing chromosome in natural populations of leishmania, the molecular karyotype of 84 leishmania stocks belonging to subgenus viannia, originating mostly from peru and bolivia, and differing according to eco-geographical and clinical parameters, was resolved and hybridised with a mini-exon probe. the results suggest that size variation of the mini-exon gene-bearing chromosome is frequent and important (up to 245-kb size-d ... | 1999 | 10428631 |
| evolution of the leishmania braziliensis species complex from amplified fragment length polymorphisms, and clinical implications. | in order to get more insight into its evolution and geographical distribution, we investigated the leishmania (viannia) braziliensis species complex using amplified fragment length polymorphisms and sequencing of a heat-shock protein 70 gene fragment. previously, several assays had alluded to the high genetic diversity of the group, and single-locus assays typically identified two species, i.e. l. braziliensis and leishmania peruviana, with occasional genetic signatures of both in the same strai ... | 2012 | 22516226 |