| heterogeneity of molecular resistance patterns in antimony-resistant field isolates of leishmania species from the western mediterranean area. | antimonials remain the first-line treatment for the various manifestations of leishmaniasis in most areas where the disease is endemic, and increasing cases of therapeutic failure associated with parasite resistance have been reported. in this study, we assessed the molecular status of 47 clinical isolates of leishmania causing visceral and cutaneous leishmaniasis from algeria, tunisia, and southern france. in total, we examined 14 genes that have been shown to exhibit significant variations in ... | 2014 | 24913173 |
| characterization of the antibody response to the saliva of phlebotomus papatasi in people living in endemic areas of cutaneous leishmaniasis. | abstract. important data obtained in mice raise the possibility that immunization against the saliva of sand flies could protect from leishmaniasis. sand fly saliva stimulates the production of specific antibodies in individuals living in endemic areas of parasite transmission. to characterize the humoral immune response against the saliva of phlebotomus papatasi in humans, we carried out a prospective study on 200 children living in areas of leishmania major transmission. we showed that 83% of ... | 2011 | 21540371 |
| first detection of leishmania killicki (kinetoplastida, trypanosomatidae) in ctenodactylus gundi (rodentia, ctenodactylidae), a possible reservoir of human cutaneous leishmaniasis in tunisia. | abstract: | 2011 | 21834996 |
| first report of natural infection in hedgehogs with leishmania major, a possible reservoir of zoonotic cutaneous leishmaniasis in algeria. | we report here the first known cases of natural infection of hedgehogs with leishmania major. cutaneous leishmaniasis is an important public health problem in the area of m'sila, a semi-arid province in algeria's northern sahara, where two species of hedgehog live, atelerix algirus and paraechinus aethiopicus. the aim of this research was to survey leishmania infection in these hedgehogs and evaluate whether they were reservoir hosts of leishmania in an endemic zoonotic focus of leishmaniasis. s ... | 2014 | 24699087 |