| leishmanicidal activities and cytotoxicities of bisnaphthoquinone analogues and naphthol derivatives from burman diospyros burmanica. | a methanol extract of the wood of diospyros burmanica, collected in burma (myanmar), was found to exhibit significant activity against leishmania major. subsequent chromatographically resolved fractionation led to the isolation of three novel bisnaphthoquinone analogues, burmanin a, b, and c (1-3), together with nine known compounds (4-12). the structure of 1 was confirmed by x-ray crystallography, and those of 2 and 3 by spectroscopic techniques, including 1d and 2d nmr. the inhibitory activiti ... | 2012 | 22858297 |
| antileishmanial compounds from cordia fragrantissima collected in burma (myanmar). | a methanol extract of the wood of cordia fragrantissima, collected in burma (myanmar), was found to exhibit significant activity against leishmania major. bioassay-guided fractionation of this extract using several chromatographic techniques afforded three new compounds (1-3) and five known compounds (4-8). the structures of the new compounds were revealed on the basis of spectroscopic data interpretation and by x-ray crystallographic analysis. interestingly, the new compounds, despite the prese ... | 2008 | 18088097 |