| population structure and geographical subdivision of the leishmania major vector phlebotomus papatasi as revealed by microsatellite variation. | multi-locus microsatellite typing (mlmt) has been employed to infer the population structure of phlebotomus papatasi (scopoli) (diptera: psychodidae) sandflies and assign individuals to populations. phlebotomus papatasi sandflies were collected from 35 sites in 15 countries. a total of 188 p. papatasi individuals were typed using five microsatellite loci, resulting in 113 different genotypes. unique microsatellite signatures were observed for some of the populations analysed. comparable results ... | 2009 | 19239616 |
| mucocutaneous leishmaniasis caused by leishmania donovani infection in an indian man. | leishmaniasis is a protozoal disease caused by species of leishmania. mucocutaneous leishmaniasis (mcl) involves the skin and mucosa. india is endemic for species such as leishmania donovani and leishmania major, which are responsible for visceral and cutaneous leishmaniasis, respectively. although mcl has been reported from india previously, the implicated pathogen was identified as l. donovani in only one case. | 2015 | 25557311 |
| A novel 12.6-kDa protein of Leishmania donovani for the diagnosis of Indian visceral leishmaniasis. | For the diagnosis of visceral leishmaniasis (VL), rK39 antigen-based rapid test is widely used. Unfortunately, up to 32% healthy individuals from endemic region test positive with this antigen. There is an urgent need to search for a more specific antigen with sensitivity similar to rK39. | 2011 | 21923256 |
| efficacy of short-duration (twice weekly) intralesional sodium stibogluconate in treatment of cutaneous leishmaniasis in india. | cutaneous leishmaniasis (cl) is caused by leishmania major and l. tropica in the old world. bikaner, the 'thar desert', situated in the north-western corner of india, is an endemic pocket for cl caused by l. tropica. skin lesions of cl heal slowly, causing disfiguring scars if remaining untreated. current recommended treatment for cl comprises systemic administration of sodium stibogluconate (ssg) for 2-3 weeks. five to seven injections of ssg intralesionally have also been found to be effective ... | 2010 | 20500797 |
| evaluation of leishmanin skin test in indian visceral leishmaniasis. | we evaluated the performance of the leishmanin skin test (lst) in 50 patients with visceral leishmaniasis (vl), 124 cured vl patients at different time intervals, 125 healthy controls from an endemic region (hec), and 14 healthy controls from a non-endemic region (nehc). the leishmanin antigen used was based on leishmania major and was obtained from the pasteur institute (iran). a positive lst was found in 14.0% of patients with active vl, 40.3% of cured patients, 21.6% of hecs, and 0% in nehcs. ... | 2009 | 19346376 |
| comment on: cutaneous leishmaniasis in nepal: leishmania major as a cause. | | 2008 | 18353409 |
| vaccination of langur monkeys (presbytis entellus) against leishmania donovani with autoclaved l. major plus bcg. | the protective potential of killed leishmania major (alm) along with bcg was evaluated against l. donovani in indian langur monkeys in single and triple dose schedules. a delayed protection was observed in monkeys after a single dose schedule of alm (3 mg)+bcg (3 mg) given intradermally 2 months before intravenous challenge with l. donovani. triple dose schedule each of 1 mg alm + 1 mg bcg was more effective. the status remained unchanged until the end of the experiment (approximately 8 months). ... | 1998 | 9550214 |