Publications

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failure of meglumine antimoniate to cure cutaneous lesions due to leishmania major in algeria. 19863544363
[detection and species identification of two imported cases of cutaneous leishmaniasis].to diagnose and identify pathogen of two suspected cases of cutaneous leishmaniasis.201124822349
[demonstration of the leishmanicidal activity of stachys guyoniana against leishmania major in eastern algeria].the authors report the results of the assessment of the leishmanicidal activity of a plant species of the lamiaceae family, stachys guyoniana. this in vitro study used the species endemic in algeria, leishmania major. both the butanolic and ethyl acetate extracts showed strong activity against this strain.201324001646
antileishmanial activity of some plants growing in algeria: juglans regia, lawsonia inermis and salvia officinalis.the current study was undertaken to evaluate in vitro the antileishmanial activity of three plants growing wild in algeria : juglans regia, lawsonia inermis and salvia officinalis. the hydroalcoholic extracts of these plants were tested on the growth of the promastigotes of leishmania major. the plant extract effects were compared with three controls : crl1 composed of 1 ml rpmi inoculated with 10(6) of promastigotes, crl2 composed of 1 ml rpmi inoculated with 10(6) of promastigotes and 100 µl o ...201324146470
[ankle and foot ulcerations in a diabetic patient revealing cutaneous leishmaniasis].cutaneous leishmaniasis is a parasitic disease that typically manifests as a typical crusted ulcer called the oriental sore. its localization on the lower limbs can be mistaken for a leg ulcer.201425201090
heterogeneity of molecular resistance patterns in antimony-resistant field isolates of leishmania species from the western mediterranean area.antimonials remain the first-line treatment for the various manifestations of leishmaniasis in most areas where the disease is endemic, and increasing cases of therapeutic failure associated with parasite resistance have been reported. in this study, we assessed the molecular status of 47 clinical isolates of leishmania causing visceral and cutaneous leishmaniasis from algeria, tunisia, and southern france. in total, we examined 14 genes that have been shown to exhibit significant variations in ...201424913173
development of a murine infection model with leishmania killicki, responsible for cutaneous leishmaniosis in algeria: application in pharmacology.in algeria, leishmania infantum, leishmania major, and leishmania killicki (leishmania tropica) are responsible for cutaneous leishmaniosis. we established a murine model of l. killicki infection to investigate its infective capacity, some immunophysiopathological aspects, and its suitability for pharmacological purposes. following the injection of l. major or l. killicki metacyclic promastigotes in the ear dermis of balb/c mice, the course of infection was followed. the infection with l. killic ...201626949705
[Spread of Leishmania major to the north of Algeria.]Since a long time, Leishmania major and L. infantum foci in Algeria were geographically separated by the mountains of the Tell Atlas which represent a natural barrier. Recently, a new focus of cutaneous leishmaniasis (CL) has emerged in the village of El M'hir, located on the north side of the chain of the Tell Atlas, in the basin of the Soummam. During the period 2004-2010, 152 CL cases have been registered and 12 isolates were obtained from patients who declared never having been outside the v ...201122170408
isolation of leishmania major yakimoff & schokhor, 1914 from psammomys obesus gretzschmar, 1828 (rodentia: gerbillidae) in algeria. 19836364474
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