| heterogeneity of molecular resistance patterns in antimony-resistant field isolates of leishmania species from the western mediterranean area. | antimonials remain the first-line treatment for the various manifestations of leishmaniasis in most areas where the disease is endemic, and increasing cases of therapeutic failure associated with parasite resistance have been reported. in this study, we assessed the molecular status of 47 clinical isolates of leishmania causing visceral and cutaneous leishmaniasis from algeria, tunisia, and southern france. in total, we examined 14 genes that have been shown to exhibit significant variations in ... | 2014 | 24913173 |
| presence of sandfly-borne phleboviruses of two antigenic complexes (sandfly fever naples virus and sandfly fever sicilian virus) in two different bio-geographical regions of tunisia demonstrated by a microneutralisation-based seroprevalence study in dogs. | sandfly-borne phleboviruses are present in north africa where they can infect humans in regions where leishmania infantum, the causative agent of zoonotic visceral leishmaniasis in the western mediterranean basin is present affecting both humans and dogs. we investigated the capacity of dogs to be used as sentinels for sandfly-borne phleboviruses as previously shown for leishmaniasis. | 2014 | 25306250 |
| [asymptomatic bearing of leishmania infantum among tunisian hiv infected patients]. | the number of visceral leishmaniasis (vl) cases is in continuous growth in mediterranean countries. in tunisia, in addition to the traditional infantile form, more and more cases in immunocompetent or immunocompromised adults have been reported. however, co-infection vl-hiv remains rare in tunisia and diagnosis of all the cases up till now has been done using traditional techniques (serology, direct examination and culture of bone marrow). however, the last years, several studies proved the grea ... | 2007 | 17888586 |
| sandflies of the phlebotomus perniciosus complex: mitochondrial introgression and a new sibling species of p. longicuspis in the moroccan rif. | the bloodsucking adult females of phlebotomus perniciosus newstead and p. longicuspis nitzulescu (diptera: psychodidae) are important vectors of the protozoan leishmania infantum nicolle (kinetoplastida: trypanosomatidae) in western mediterranean countries. the species status of the two phlebotomine sandflies was assessed, along with the epidemiological implications. individual sandflies from three moroccan rif populations were characterized morphologically, isoenzymatically (by the isoelectrofo ... | 2004 | 15009443 |
| morphological and isoenzymatic differentiation of sympatric populations of phlebotomus perniciosus and phlebotomus longicuspis (diptera: psychodidae) in northern morocco. | the phlebotomine sandfly phlebotomus perniciosus newstead is a vector of leishmania infantum nicolle in the western mediterranean basin. in northern morocco it is often caught in sympatry with a closely related species, p. longicuspis nitzulescu. in the locality of chefchaouene where females of both species were morphologically distinguishable, none of the collected males exhibited forked copulatory valves, which is considered a specific character for p. perniciosus. they 1st were identified as ... | 1999 | 10071503 |
| phlebotominae (diptera: psychodidae) of human leishmaniosis sites in tunisia. | in order to identify the phlebotomine sandfly populations in tunisian leishmaniosis foci, an entomological survey was carried out through three entomological seasons (2002-2003-2004) in 19 visceral and cutaneous leishmaniosis areas, located in six bioclimatic zones. sandfly collections were based on light and sticky traps placed around human leishmaniosis cases. 8,722 phlebotomine sandflies belonging to 12 species were collected. the dominance of subgenus larroussius species in northern foci, ph ... | 2006 | 16605064 |
| [localized cutaneous leishmaniasis due to leishmania infantum mon-1 contracted in northern algeria]. | classically, the agent of the sporadic skin leishmaniasis in northern algeria is leishmania infantum mon-24. this paper reports the first documented observation of localized cutaneous leishmaniasis due to leishmania infantum zymodeme mon-1 in northern algeria. the interest of using the western blot serological analysis to guide the diagnosis and the usefulness of the hamster inoculation to isolate leishmania from pauciparasitized lesion is demonstrated. | 1998 | 9642468 |