Publications

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in vitro screening of traditional south african malaria remedies against trypanosoma brucei rhodesiense, trypanosoma cruzi, leishmania donovani, and plasmodium falciparum.three hundred extracts were prepared from plants traditionally used in south africa to treat malaria and screened in vitro for activity against trypanosoma brucei rhodesiense, trypanosoma cruzi, leishmania donovani, and plasmodium falciparum. for the 43 extracts which inhibited the growth of one or more parasites to more than 95 % at 9.7 µg/ml, the ic (50) values against all four protozoal parasites and cytotoxic ic (50)s against rat myoblast l6 cells were determined. amongst the most notable re ...201121412695
antiprotozoal screening of 60 south african plants, and the identification of the antitrypanosomal germacranolides schkuhrin i and ii.two hundred and seven extracts were prepared from sixty plants from south africa and screened for in vitro activity against trypanosoma brucei rhodesiense, trypanosoma cruzi, leishmania donovani, and plasmodium falciparum. for the 21 extracts which inhibited the growth of one or more parasites with more than 95 % at 10 µg/ml, the ic50 values against all four protozoal parasites and cytotoxic ic50 values against l6 myoblasts were determined. amongst the most notable results are the activities of ...201323929246
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