in vitro antiprotozoal activities and cytotoxicity of some selected cameroonian medicinal plants.eight extracts from seven selected cameroonian medicinal plants, traditionally used to treat malaria and other protozoal diseases, were tested in vitro for their antiprotozoal activities against plasmodium falciparum k1 chloroquine-resistant strain, leishmania donovani, trypanosoma cruzi and trypanosoma brucei rhodesiense, protozoa responsible for malaria, visceral leishmaniasis, chagas disease and african trypanosomiasis, respectively. the most active extract against plasmodium falciparum k1 st ...200717141994
in vitro leishmanicidal activity of some cameroonian medicinal plants.eleven plants used in the cameroonian traditional medicine for the treatment of some parasitic infections were tested for their activity on the promastigote form of leishmania donovani. after incubation with different plant extracts at doses of 1600, 800, 400 and 200 microgram/ml, the evaluation of the cell viability was done by the trypan blue exclusion technique and by flow cytometry. this study shows that 48 h after incubation of promastigotes with plant extract, solanocia mannii and solanum ...201323562881
trypanocidal and antileishmanial dihydrochelerythrine derivatives from garcinia lucida.three benzo[ c]phenanthridine alkaloids have been isolated from the stem bark of garcinia lucida: dihydrochelerythrine ( 1), 6-acetonyldihydrochelerythrine ( 2), and its new derivative, ( s)1''-(9,10-dihydro-2',3'-dihydroxy-7,8-dimethoxy-10-methyl-1,2-benzophenanthridin-9-yl)propan-2''-one (lucidamine a) ( 3). the new diisoprenylated derivative of lucidamine b ( 4) was obtained by semisynthesis. these dihydrochelerythrine derivatives as well as the crude extract displayed attractive antiprotozoa ...200717880175
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