| long-lasting protection against canine visceral leishmaniasis using the liesap-mdp vaccine in endemic areas of france: double-blind randomised efficacy field trial. | vaccination against visceral leishmaniasis has received limited attention compared with cutaneous leishmaniasis, although the need for an effective vaccine against visceral leishmaniasis is pressing. dogs constitute the major reservoir of leishmania infantum/chagasi responsible for human visceral leishmaniasis. we have recently demonstrated that the combination of naturally excreted/secreted antigens, easily purified from culture supernatant of leishmania infantum promastigotes (liesap) as vacci ... | 2007 | 17395339 |
| leishmania infantum: lipophosphoglycan intraspecific variation and interaction with vertebrate and invertebrate hosts. | interspecies variations in lipophosphoglycan (lpg) have been the focus of intense study over the years due its role in specificity during sand fly-leishmania interaction. this cell surface glycoconjugate is highly polymorphic among species with variations in sugars that branch off the conserved gal(β1,4)man(α1)-po(4) backbone of repeat units. however, the degree of intraspecies polymorphism in lpg of leishmania infantum (syn. leishmania chagasi) is not known. in this study, intraspecific variati ... | 2010 | 21118695 |