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human classical monocytes control the intracellular stage of leishmania braziliensis by reactive oxygen species.leishmania braziliensis are intracellular parasites that cause unique clinical forms of cutaneous leishmaniasis. previous studies with other leishmania species demonstrated that reactive oxygen species (ros) control promastigotes, the infective stage of the parasite, but not the amastigote form that exists in the mammalian host. here we show that ros inhibits growth of l. braziliensis amastigotes in resting monocytes, and that classical monocytes are primarily responsible for this control. ros, ...201424403561
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