| multi-site dna polymorphism analyses of leishmania isolates define their genotypes predicting clinical epidemiology of leishmaniasis in a specific region. | leishmania isolates from 57 cases of human cutaneous (cl), human visceral (vl), and canine visceral (cvl) leishmaniasis in turkey were grouped by multi-site dna polymorphism analyses into five genotypes. the initial grouping was based on dna heterogeneity of the faster-evolving mitochondrion (kinetoplast) minicircles and the intergenic regions of two nuclear repetitive genes. taxonomic affiliation and phylogenetic relationships of the five genotypes were inferred by comparing them with reference ... | 2000 | 11128706 |
| detection of leishmania major and leishmania tropica in domestic cats in the ege region of turkey. | leishmaniosis is a group of diseases caused by different species of leishmania parasites in mammalian species. the aim of the present study was to investigate the presence of leishmania spp. dna in cats using real time polymerase chain reaction (rt-pcr) assays targeting internal transcribed spacer (its1) and heat-shock protein 70 gene (hsp70) regions with leishmania species-specific primers and probes. blood samples were collected from 147 cats (73 female; 74 male) in the endemic regions for zoo ... | 2015 | 26277567 |
| the emergence of leishmania major and leishmania donovani in southern turkey. | in southern turkey, leishmania tropica and l. infantum are both the causative agents of cutaneous leishmaniasis (cl) and visceral leishmaniasis (vl), respectively. however, l. major and l. donovani were known to exist after the influx of syrian refugees. | 2014 | 24449479 |
| natural hybrid of leishmania infantum/l. donovani: development in phlebotomus tobbi, p. perniciosus and lutzomyia longipalpis and comparison with non-hybrid strains differing in tissue tropism. | infection caused by parasites from l. donovani complex can manifest as a serious visceral disease or a self-healing milder cutaneous form. the different tropism and pathology in humans is caused by the interaction between parasites, host and vector determinants but the mechanisms are not well understood. in cukurova region in turkey we previously identified a major focus of cutaneous leishmaniasis caused by l. donovani/infantum hybrids (cuk strain) and isolated this parasite from the locally abu ... | 2015 | 26608249 |