| a comparison of promastigote and amastigote antigens of leishmania infantum in the diagnosis of visceral leishmaniosis by elisa and ifa tests in turkey. | this study was designed to evaluate the elisa and ifa tests for diagnosis of visceral leishmaniosis (vl) using soluble and crude antigens from promastigote and amastigote forms of leishmania infantum. a total of 70 sera were tested, including 30 patients who were suspected for leishmaniosis (10 healthy persons, 10 patients with toxoplasmosis, 10 patients with giardiosis). in the 30 patients suspected to have leishmaniosis, smears were prepared from bone marrow aspirates and all material aspirate ... | 1997 | 17265631 |
| visceral leishmaniasis in 13 pediatric patients in turkey: treatment experience. | visceral leishmaniasis (vl) is a life-threatening systemic infection caused by protozoa of the genus leishmania and transmitted by phlebotomine sandflies. leishmaniases are widespread in most countries in the mediterranean basin, including turkey. leishmania infantum is responsible for vl in turkey. we previously reported 19 children with vl who were diagnosed during the period of january 2000 to december 2003. in this study, 13 consecutive cases of vl admitted to our hospital between december 2 ... | 2009 | 20101572 |
| natural hybrid of leishmania infantum/l. donovani: development in phlebotomus tobbi, p. perniciosus and lutzomyia longipalpis and comparison with non-hybrid strains differing in tissue tropism. | infection caused by parasites from l. donovani complex can manifest as a serious visceral disease or a self-healing milder cutaneous form. the different tropism and pathology in humans is caused by the interaction between parasites, host and vector determinants but the mechanisms are not well understood. in cukurova region in turkey we previously identified a major focus of cutaneous leishmaniasis caused by l. donovani/infantum hybrids (cuk strain) and isolated this parasite from the locally abu ... | 2015 | 26608249 |
| genetic diversity and structure in leishmania infantum populations from southeastern europe revealed by microsatellite analysis. | the dynamic re-emergence of visceral leishmaniasis (vl) in south europe and the northward shift to leishmania-free european countries are well-documented. however, the epidemiology of vl due to leishmania infantum in southeastern (se) europe and the balkans is inadequately examined. herein, we aim to re-evaluate and compare the population structure of l. infantum in se and southwestern (sw) europe. | 2013 | 24308691 |
| genomic confirmation of hybridisation and recent inbreeding in a vector-isolated leishmania population. | although asexual reproduction via clonal propagation has been proposed as the principal reproductive mechanism across parasitic protozoa of the leishmania genus, sexual recombination has long been suspected, based on hybrid marker profiles detected in field isolates from different geographical locations. the recent experimental demonstration of a sexual cycle in leishmania within sand flies has confirmed the occurrence of hybridisation, but knowledge of the parasite life cycle in the wild still ... | 2014 | 24453988 |
| clinical manifestations and genetic variation of leishmania infantum and leishmania tropica in southern turkey. | l. infantum was isolated from cutaneous leishmaniasis (cl) skin lesions in patients having no signs and symptoms of visceral leishmaniasis (vl). similarly, l. tropica had previously been isolated from patients with vl in the absence of cutaneous lesions. it was not certain how visceralization occurred. smears (207) and bone marrow samples (135) were taken from cl and vl-suspected patients, respectively. microscopic examination, its1-pcr, rflp and dna sequencing for all samples were analyzed. the ... | 2015 | 25913665 |
| risk factors for cutaneous leishmaniasis in cukurova region, turkey. | we conducted a case-control study to evaluate risk factors for cutaneous leishmaniasis caused by leishmania infantum outbreaks in villages in the cukurova region, south anatolia, turkey. 282 respondents from eight villages were interviewed using structured questionnaires. epidemiological and clinical characteristics, personal protection and knowledge of leishmania were analyzed. young people, aged from 5-19 years, were found to be the most endangered group of villagers. the concurrent presence o ... | 2012 | 22284721 |
| cutaneous leishmaniasis caused by leishmania infantum transmitted by phlebotomus tobbi. | transmission of cutaneous leishmaniasis (cl) caused by leishmania infantum was studied in south anatolia, turkey. small, non-ulcerating lesions prevailed and patients were negative in rk39 tests for antibody detection for human visceral leishmaniasis (vl). the most abundant sand fly species, phlebotomus tobbi, was found positive for leishmania promastigotes with a prevalence of 1.4% (13 out of 898 dissected females). the isolated strains were identical with those obtained from patients with cl a ... | 2009 | 18761342 |
| the infection risk of visceral leishmaniasis among household members of active patients. | human visceral leishmaniasis (hvl), caused by leishmania infantum is mainly observed as sporadic cases in turkey and dogs are considered as the main reservoir of the disease. the incidence of visceral leishmaniasis among members of households where a hvl infection has already been diagnosed was studied in clusters around the diagnosed cases in different regions in turkey. a total of 47 serum samples collected from the households of 11 proven visceral leishmaniasis patients were screened for anti ... | 2006 | 16412686 |
| leishmaniasis in turkey. | leishmaniases are widespread in most countries in the mediterranean basin, including turkey. two forms are observed in turkey; leishmania infantum is responsible from visceral leishmaniasis (vl), and l. tropica causes cutaneous leishmaniasis (cl). phlebotomus sergenti, p. papatasi, p. major and p. syriacus are considered to be the probable vectors, and dogs are the main reservoir of l. infantum, while p. sergenti is the main suspected vector of l. tropica.vl is sporadically seen mainly in the ae ... | 2002 | 12387909 |
| evaluation of conjunctival swab sampling in the diagnosis of canine leishmaniasis: a two-year follow-up study in çukurova plain, turkey. | the diagnosis of canine leishmaniasis (canl) in symptomatic and asymptomatic dogs is a very important and problematic public health issue in turkey. a longitudinal study was carried out on dogs in selected villages in the çukurova plain in turkey, from july 2011 to june 2013, where cutaneous (cl) and visceral (vl) leishmaniasis is endemic. the study aimed to determine the prevalence of canl and to evaluate the early diagnostic performance of the non-invasive conjunctival swab nested pcr (cs n-pc ... | 2015 | 26415899 |