| the story of the identification of leishmania tropica as the cause of the cambay sore and of its development in culture demonstrated for the first time in india and subsequent research on the subject. | | 1951 | 24541011 |
| long-term efficacy of single-dose radiofrequency-induced heat therapy vs. intralesional antimonials for cutaneous leishmaniasis in india. | radiofrequency-induced heat therapy (rfht) has been found to be safe and effective against cutaneous leishmaniasis (cl) in the short term, but its long-term efficacy is unclear. | 2013 | 23298394 |
| rflps of its, its1 and hsp70 amplicons and sequencing of its1 of recent clinical isolates of kala-azar from india and bangladesh confirms the association of l. tropica with the disease. | visceral leishmaniasis or kala-azar (ka) is a serious health concern in india. in the present study, restriction fragment length polymorphism (rflp) of three genetic markers viz., internal transcribed spacer (its), its1 and heat shock protein 70 (hsp70) have been employed for typing the clinical isolates [n=15] of ka and post kala-azar dermal leishmaniosis (pkdl) collected from india and bangladesh in the period of 2006-2010. experimentally, its, its1 and hsp70 regions of genomes of all the clin ... | 2012 | 22960646 |
| a patient presenting with diffuse cutaneous leishmaniasis (dcl) as a first indicator of hiv infection in india. | opportunistic parasitic infections such as leishmaniasis are common in human immunodeficiency virus (hiv)-infected patients and are usually acquired several days after initial diagnosis of hiv infection. here, we report on a patient who presented with diffuse cutaneous leishmaniasis (dcl) caused by leishmania tropica as the first and only clinical manifestation of hiv infection. to the best of our knowledge, this is the first case that illustrates that dcl could be the first clinical indicator o ... | 2011 | 21734126 |
| evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by leishmania tropica: interleukin-8, monocyte chemotactic protein-1 and nitric oxide are major regulatory factors. | we have established leishmania tropica as the causative agent of cutaneous leishmaniasis (cl) in the region of india where the disease is endemic. the association between localized and circulating levels of immune-determinants in cl patients was evaluated. reverse transcription-polymerase chain reaction analysis revealed up-regulation of interferon-gamma (ifn-gamma), interleukin (il)-1beta, il-8, tumour necrosis factor-alpha (tnf-alpha), il-10 and il-4 in dermal lesions at the pretreatment stage ... | 2010 | 20102417 |
| indian kala-azar caused by leishmania tropica. | kala-azar, or visceral leishmaniasis, in india is generally assumed to be a result of infection with leishmania donovani. 15 parasite isolates collected over the past 10 years from patients with classical disease were typed by monoclonal antibodies, isoenzymes, and kdna analysis. 4 were shown to be l tropica, a species historically associated with cutaneous disease and more recently a mild "visceralising" disease from the desert storm experience. the results confirm that l tropica is a co-endemi ... | 1995 | 7715298 |
| cultivation of leishmania tropica from untreated and treated cases of oriental sore. | | 1982 | 7129588 |
| a comparison of five selective media for the primary isolation of leishmania strains in india. | leishmania parasites of the three distinct pathogenic forms of indian origin (cutaneous, visceral and post kala-azar dermal leishmaniasis) were assessed with five selective media for their rate of primary isolation. leishmania donovani strains showed the higher rate of isolation in modified tobie's medium, and leishmania tropica in tobie's with fcs. however, strains of post kala-azar dermal leishmaniasis (pkdl) showed 100% isolation in schneider's with fcs medium. but as a whole modified tobie's ... | 1987 | 3432954 |
| excreted factors and membrane-associated carbohydrates of indian leishmaniae. | antigenic identity between the cell surface carbohydrate ligands and their excreted factor (ef) in all forms of indian leishmaniasis were assessed by 11 carbohydrate-specific lectins. our results demonstrated that 3 lectins, viz. pna, sba and wfa showed unique selectivity towards skin-dwelling parasites. the efs of visceral leishmaniasis (vl), post-kala-azar dermal leishmaniasis (pkdl) and cutaneous leishmaniasis (cl) formed band against cona at 1000, and 500 micrograms/ml concentration, respect ... | 1988 | 3238471 |