retrospective survey of chikungunya disease in réunion island hospital staff.réunion island (indian ocean) has been suffering from its first known chikungunya virus (chikv) epidemic since february 2005. to achieve a better understanding of the disease, a questionnaire was drawn up for hospital staff members and their household. chikv infected about one-third of the studied population, the proportion increasing with age and being higher in women. presence of a garden was associated with chikv infection. the geographical distribution of cases was concordant with insect vec ...200817433130
a single mutation in chikungunya virus affects vector specificity and epidemic potential.chikungunya virus (chikv) is an emerging arbovirus associated with several recent large-scale epidemics. the 2005-2006 epidemic on reunion island that resulted in approximately 266,000 human cases was associated with a strain of chikv with a mutation in the envelope protein gene (e1-a226v). to test the hypothesis that this mutation in the epidemic chikv (strain lr2006 opy1) might influence fitness for different vector species, viral infectivity, dissemination, and transmission of chikv were comp ...200718069894
post-epidemic chikungunya disease on reunion island: course of rheumatic manifestations and associated factors over a 15-month period.although the acute manifestations of chikungunya virus (chikv) illness are well-documented, few data exist about the long-term rheumatic outcomes of chikv-infected patients. we undertook between june and september 2006 a retrospective cohort study aimed at assessing the course of late rheumatic manifestations and investigating potential risk factors associated with the persistence of these rheumatic manifestations over 15 months. 147 participants (>16 yrs) with laboratory-confirmed chikv disease ...200919274071
identical strength of the t cell responses against e2, nsp1 and capsid chikv proteins in recovered and chronic patients after the epidemics of 2005-2006 in la reunion characterize the immunity developed by patients infected by chikungunya virus (chikv), we studied the intensity and specificity of chikv-specific t cells mediated responses in chronic and recovered patients at 12 to 24 months post-infection. t cells were challenged in vitro against chikv synthetic peptides covering the length of three viral proteins, capsid, e2 and nsp1 proteins as well as all inactivated virus particles. cytokine production was assessed by elispot and intracellular labeling. ...201324376836
[updated inventory of mosquitoes (diptera: culicidae) of the island of la réunion, indian ocean].a literature analysis coupled with new entomological surveys conducted between 2009 and 2012 led to changes in the list of mosquito species present on the island of la réunion. using morphological criteria, orthopodomyia arboricollis is replaced by or. reunionensis. on the basis of morphometrical and genetic criteria, culex univittatus is replaced by cx. neavei. cx. poicilipes, which was already reported missing 40 years ago, has not been found again. anopheles arabiensis is confirmed as the onl ...201323681758
[the concept of emerging viral diseases: what risk for reunion island?].in reunion island, the risk of emerging infectious diseases lies mainly in several viral zoonoses: west nile fever, sindbis virus, nipah virus, wesselsbron virus, rift valley fever and japanese encephalitis. there morbidity and consequences are more or less important but they all have a non-negligible epidemic potential, so they have to be monitored. indeed, the struggle against these emerging infectious diseases requires an early detection of the cases, thus a surveillance system capable of det ...201323765703
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