Publications

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comparative attractiveness of co(2)-baited cdc light traps and animal baits to phlebotomus duboscqi sandflies.in order to understand sandfly bionomics, vector species identification, and to develop methods for sandfly control, there is a need to sample sandflies in any particular habitat. this survey was aimed at determining the best method of sampling phlebotomus (phlebotomus) duboscqi (diptera: psychodidae) in the field.200919724082
zoophilic feeding behaviour of phlebotomine sand flies in the endemic areas of cutaneous leishmaniasis of sindh province, pakistan.leishmania (leishmania) major has been identified as the major causative agent of cutaneous leishmaniasis in sindh province of southern pakistan. to make a rational approach for understanding the pathogen transmission cycles, the sand fly species and their natural blood meals in the endemic areas were examined. total dna was individually extracted from sand flies collected in four villages in sindh province. pcr-rflp (restriction fragment length polymorphism) and sequence analysis of the 18s rib ...201222246369
experimental infection of domestic goats with leishmania major through bites of infected phlebotomus duboscqi and needle inoculation of culture-derived promastigotes. 19947831760
endogenous il-12 is required for control of th2 cytokine responses capable of exacerbating leishmaniasis in normally resistant mice.we investigated the mechanisms by which treatment with anti-il-12 ab prevents cure of infection with leishmania major in resistant c57bl/6 mice. consistent with delayed production of il-12, anti-il-12 abs could be administered as late as 2 wk after infection to exacerbate disease. starting at 2 wk of infection, the cultured lymph node cells from mice treated with either polyclonal or monoclonal anti-il-12 abs persistently generated 3- to 10-fold more il-4 and il-10 in response to l. major ag com ...19957608551
bionomics of phlebotomus papatasi (diptera: psychodidae) in an endemic focus of zoonotic cutaneous leishmaniasis in central iran.following an epidemiological survey of zoonotic cutaneous leishmaniasis (zcl) in several villages of badrood, a rural district north of the city of natanz, central iran, phlebotomus (phlebotomus) papatasi scopoli were found to be naturally infected with leishmania (leishmania) major zymodeme mon-26. sand flies were collected and dissected biweekly from rodent burrows from may to october 2001. leptomonad infection rates varied between 6.7% and 22.0%, being greatest in september, coinciding with p ...200516007964
cloning and characterization of a gene encoding an immunoglobulin-binding receptor on the cell surface of some members of the family trypanosomatidae.several members of the trypanosomatidae family, when freshly isolated from their mammalian hosts, have immunoglobulins adsorbed to their cell surfaces. however, a significant portion of these antibody molecules is not parasite specific, i.e., the immunoglobulins are bound to the parasite's cell surface molecules via noncognitive interactions. it has been proposed that this noncognitive adsorption of immunoglobulins to the parasite is mediated by an fc-like receptor present in several members of ...200312933849
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