| promiscuous prediction and conservancy analysis of ctl binding epitopes of hcv 3a viral proteome from punjab pakistan: an in silico approach. | hcv is a positive sense rna virus affecting approximately 180 million people world wide and about 10 million pakistani populations. hcv genotype 3a is the major cause of infection in pakistani population. one of the major problems of hcv infection especially in the developing countries that limits the limits the antiviral therapy is the long term treatment, high dosage and side effects. studies of antigenic epitopes of viral sequences of a specific origin can provide an effective way to overcome ... | 2011 | 21303499 |
| introduction and evolution of dengue virus type 2 in pakistan: a phylogeographic analysis. | pattern of dengue periodic epidemics through the years along with sporadic cases of dengue hemorrhagic fever followed by a severe 2011 epidemic of dengue fever in pakistan make pakistan a dengue endemic country. to study the entry and evolution of dengue virus serotype 2 (denv-2) in pakistan, we sequenced three full length genomes and 24 complete envelope sequences of denv-2 from the years 2010, 2011 and 2013 collected from punjab province of pakistan. | 2015 | 26395339 |
| evolution and heterogeneity of multiple serotypes of dengue virus in pakistan, 2006-2011. | even though dengue has been recognized as one of the major public health threats in pakistan, the understanding of its molecular epidemiology is still limited. the genotypic diversity of dengue virus (denv) serotypes involved in dengue outbreaks since 2005 in pakistan is not well studied. here, we investigated the origin, diversity, genetic relationships and geographic distribution of denv to understand virus evolution during the recent expansion of dengue in pakistan. | 2013 | 24007412 |