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whole genome sequencing-based molecular epidemiologic analysis of autochthonous dengue virus type 1 strains circulating in japan in 2014.cases of autochthonous infections of dengue virus type 1 (denv-1) were detected in japan after a 70-year period devoid of dengue outbreaks. we previously showed that e gene sequences are identical in 11 of the 12 denv-1 strains autochthonous to japan. however, the e sequence represents only 14% of the denv-1 genome. in the present study, we have sequenced the entire genome of 6 autochthonous denv-1 strains that were isolated from patients during the 2014 outbreak. sequencing of 5 yoyogi group st ...201727169954
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