| antigenic and molecular characterization of bat rabies virus in europe. | the predominant role of eptesicus serotinus in the epizootic of bat rabies in europe was further outlined by the first isolation of the rabies virus from this species in france. the distribution of the virus was studied in naturally infected e. serotinus bats at the time of death and suggested that the papillae of the tongue and the respiratory mucosa may play a role in virus production and excretion. the analysis of 501 french rabies virus isolates from various animal species by antinucleocapsi ... | 1992 | 1401009 |
| a reduced panel of anti-nucleocapsid monoclonal antibodies for bat rabies virus identification in europe. | a reduced panel of 4 anti-nucleocapsid monoclonal antibodies (mab) was set up to distinguish viruses of terrestrial mammal origin from viruses of bat origin in europe. four additional mab were necessary to identify each one of the four serotypes of lyssavirus. these 8 mab were selected out of 25 mab secreted by hybridomas obtained from mice immunized with either serotype 1 lyssavirus (rabies virus pv4) or serotype 3 lyssavirus (mokola). they were screened with 32 viruses representative of the fo ... | 1990 | 2277871 |
| efficacy of rabies vaccines against duvenhage virus isolated from european house bats (eptesicus serotinus), classic rabies and rabies-related viruses. | isolates of rabies from separate enzootics can be distinguished by their reactions with panels of monoclonal antibodies (mabs) directed to different sites on the nucleocapsid and glycoproteins of the virus. estimates of antigenic relatedness can be made by comparing similarities among groups. in this manner it can be shown that while classic strains of rabies react with most of the mabs, the rabies related lyssaviruses (mokola, lagos and duvenhage) react with only a few of the mabs and isolates ... | 1988 | 3245296 |
| pathogenesis of rabies virus from a danish bat (eptesicus serotinus): neuronal changes suggestive of spongiosis. | rabies virus strains isolated from a european bat (eptesicus serotinus) in denmark (dbv), a north american big brown bat (eptesicus fuscus) in new york state (ny-bat), and a human in south africa (duvenhage strain (duv-1) were studied by using a panel of monoclonal antibodies and by inoculating mice, cats, and dogs. the ten danish virus isolates from the same bat species reacted identically with a panel of monoclonal antibodies. immunofluorescence, monoclonal antibody, and histopathologic studie ... | 1988 | 3369944 |
| [antigenic determination of human anti-rabies vaccine against viral street strains common in the wild animal population in poland]. | the aim of the study was to compare the antigen properties of a vaccine strain with street strains isolated from various animal hosts throughout the country. investigation was carried out using monoclonal antibodies against nc protein. also, two tests were carried out: the modified nih test for potency and the neutralization test using the sera of people vaccinated against rabies (pm vaccine strain). the investigated street strains were used in both tests as the challenge viruses. a suspension o ... | 1994 | 7541494 |
| ten-year survey of british bats for the existence of rabies. | in 1985, a notable increase in the number of recorded cases of rabies in european bats was observed, indicating a possible spread of the rabies virus in these bats. because of concern that the disease could be introduced into the united kingdom by bats crossing from mainland europe, a programme of screening dead bats for the presence of rabies and rabies-related viruses was initiated at the rabies research and diagnostic unit at the central veterinary laboratory. over a period of 10 years (janua ... | 1996 | 8950819 |
| public health awareness of emerging zoonotic viruses of bats: a european perspective. | bats classified in the order chiroptera are the most abundant and widely distributed non-human mammalian species in the world. several bat species are reservoir hosts of zoonotic viruses and therefore can be a public health hazard. lyssaviruses of different genotypes have emerged from bats in america (genotype 1 rabies virus; rabv), europe (european bat lyssavirus; eblv), and australia (australian bat lyssavirus; ablv), whereas nipah virus is the most important recent zoonosis of bat origin in a ... | 2006 | 17187565 |
| [bat rabies in europe and the czech republic]. | in 2005, six children were treated in our department who had been in contact with a bat infected with european bat lyssavirus 1 (ebl1). in the czech republic, this was the first confirmed case of rabies since 2002, but the fourth case of bat rabies since 1994. all the cases were related to southern moravia and bat species which almost do not migrate. this suggests only endemic prevalence of ebl1 in this country. bat rabies is different from rabies in terrestic mammals. based on genetic analyses, ... | 2007 | 17703400 |
| experimental infection of foxes with european bat lyssaviruses type-1 and -2. | experimental studies have been undertaken to assess the susceptibility of silver foxes to bat variants of rabies virus, namely european bat lyssaviruses (eblvs). both eblv-1 and eblv-2 have been isolated in european bats since 1954, in eptesicus serotinus and myotis species, respectively. since 2000, the number of reported cases has increased largely due to the improvement of the surveillance of bat rabies virus throughout europe. although over >800 eblvs cases have been reported in bats in euro ... | 2008 | 18634496 |
| active surveillance of bat rabies in france: a 5-year study (2004-2009). | active surveillance of bats in france started in 2004 with an analysis of 18 of the 45 bat species reported in europe. rabies antibodies were detected in six indigenous species, mainly in eptesicus serotinus and myotis myotis, suggesting previous contact with the eblv-1 rabies virus. nineteen of the 177 tested bats were shown serologically positive in seven sites, particularly in central and south-western france. neither infectious viral particles nor viral genomes were detected in 173 and 308 t ... | 2011 | 21570221 |
| favourable outcome in a patient bitten by a rabid bat infected with the european bat lyssavirus-1. | the classic rabies virus (genotype 1) has been eliminated in western europe, but related lyssaviruses still circulate in local bats. in august 2010, a belgian photographer was bitten upon provocation of a disoriented eptesicus serotinus bat in spain. the bat was infected with european bat lyssavirus-1 (genotype 5). the isolate proved highly neurovirulent in mice. the patient had received preventive rabies immunisations years before the incident and received two boosters with the hdcv rabies vacc ... | 2016 | 23627196 |