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purification, physicochemical characterization and biological properties of a lectin from erythrina velutina forma aurantiaca seeds.a lectin was purified from seeds of erythrina velutina forma aurantiaca by affinity chromatography on cross-linked guar gum. the lectin is a potent agglutinin for human (minimal concentration of protein able to cause visible agglutination of a 2% erythrocyte suspension varying from 1 to 4 micrograms/ml), rabbit (4 micrograms/ml) and chicken erythrocytes (8 micrograms/ml) but presented low activity against cow (250 micrograms/ml) or sheep (333 micrograms/ml) blood cells. hemagglutination of human ...19969181078
central nervous system effects of the crude extract of erythrina velutina on rodents.the aqueous extract (ae) of erythrina velutina prolonged the sleep duration induced by sodium pentobarbital (control: 6.4 +/- 1.2 min; extract 10 mg/kg, 47.1 +/- 3.9 min; extract 100 mg/kg, 109.4 +/- 7.2 min; f = 243, p < 0.001). in the open field, the extract at the doses of 10 and 50 mg/kg did not changed the number of crossings, rearings nor groomings. on the other hand, at the dose of 200 mg/kg it reduced the number of crossings (q = 6.25, p < 0.05) and groomings (q = 3.91, p < 0.05). when e ...200415261973
effect of erythrina velutina and erythrina mulungu in rats submitted to animal models of anxiety and depression.erythrina velutina (ev) and erythrina mulungu (em), popularly used in brazil as tranquilizing agents, were studied. the effects of acute and chronic oral treatment with a water:alcohol extract of ev (7:3, plant grounded stem bark; acute = 100, 200, 400 mg/kg; chronic = 50, 100, 200 mg/kg) were evaluated in rats (n = 11-12) submitted to the elevated t-maze (for avoidance and escape measurements) model of anxiety. this model was selected for its presumed capacity to elicit specific subtypes of anx ...200616470314
anxiolytic-like effect of chronic treatment with erythrina velutina extract in the elevated plus-maze test.in brazil, erythrina velutina (fabaceae) is widely used as a tranquilizer and/or sedative, and its extract exerts an anxiolytic-like effect profile in animal models, although these results may be caused by its sedative or amnesic effects. aims, materials and methods: thus, this study evaluated the effect of acute and chronic (23-26 days) administrations of the hydroalcoholic extract of the stem bark of erythrina velutina (orally) in mice submitted to the following tests: elevated plus-maze, forc ...200818550307
evidence of the mechanism of action of erythrina velutina willd (fabaceae) leaves aqueous extract.erythrina velutina is traditionally used for sleepiness, convulsions and nervous system excitation in brazil. although central effects have been reported for erythrina velutina, little is known about its mechanism of action.200919146942
evaluation of seed extracts from plants found in the caatinga biome for the control of aedes aegypti.dengue fever, currently the most important arbovirus, is transmitted by the bite of the aedes aegypti mosquito. given the absence of a prophylactic vaccine, the disease can only be controlled by combating the vector insect. however, increasing reports of resistance and environmental damage caused by insecticides have led to the urgent search for new safer alternatives. in this regard, plants stand out as a source of easy-to-obtain biodegradable insecticide molecules. twenty (20) plant seed extra ...201425056942
anticonvulsant activity of hydroalcoholic extracts from erythrina velutina and erythrina mulungu.the anticonvulsant effects of hydroalcoholic extracts (haes) from the stem bark of erythrina velutina and erythrina mulungu on pentylenetetrazole (ptz) and strychnine-induced seizure tests and the potentiation of pentobarbital-induced sleeping time in mice with the extracts were examined in this study. these medicinal plants belong to the fabaceae family and are popularly used in brazil for their effects on the central nervous system. the extracts of erythrina velutina (intraperitoneally or oral ...200717070003
anti-nociceptive activity of the aqueous extract of erythrina velutina leaves.anti-nociceptive and anti-oedematogenic effects of the aqueous extract from the leaves of erythrina velutina were tested through experimental models of nociception in mice and paw oedema induced by carrageenin in rats. the extract (300 and 600 mg/kg) did not change the carrageenin-induced paw oedema. in the hot plate test the extract also did not alter the latency time for mice liking the rear paws. moreover, the extract (600 mg/kg) decreased by 96.5% the paw liking time in the second phase of t ...200516242270
the positive inotropic effect of the ethyl acetate fraction from erythrina velutina leaves on the mammalian myocardium: the role of adrenergic receptors.we studied the effects of ethyl acetate fraction (eacf) obtained from erythrina velutina leaves on mammalian myocardium.201323647686
dormancy as exaptation to protect mimetic seeds against deterioration before dispersal.mimetic seeds simulate the appearance of fleshy fruits and arilled seeds without producing nutritive tissues as a reward for seed dispersers. in this strategy of seed dispersal, seeds may remain attached to the mother plant for long periods after maturity, increasing their availability to naïve seed dispersers. the hypothesis that seed coat impermeability in many tropical fabaceae with mimetic seeds serves as an exaptation to protect the seeds from deterioration and rotting while awaiting disper ...201020354070
hypaphorine, an indole alkaloid from erythrina velutina, induced sleep on normal mice.an indole alkaloid (hypaphorine (1)) was isolated from brazilian medicinal plant, erythrina velutina (leguminosae). this compound was investigated for sleep promoting effects in mice, and the results showed that it significantly increased non-rapid eye movement (nrem) sleep time during the first hour after its administration. the nrem sleep time was enhanced by 33% in the experimental mice when compared to that of the controls. this study therefore confirmed its sleep promoting property.200818571406
microbial activity, arbuscular mycorrhizal fungi and inoculation of woody plants in lead contaminated soil.the goals of this study were to evaluate the microbial activity, arbuscular mycorrhizal fungi and inoculation of woody plants (caesalpinia ferrea, mimosa tenuiflora and erythrina velutina) in lead contaminated soil from the semi-arid region of northeastern of brazil (belo jardim, pernambuco). dilutions were prepared by adding lead contaminated soil (270 mg kg(-1)) to uncontaminated soil (37 mg pb kg soil(-1)) in the proportions of 7.5%, 15%, and 30% (v:v). the increase of lead contamination in t ...201124031701
in vitro and ex vivo anticholinesterase activities of erythrina velutina leaf extracts.erythrina velutina (ev) willd (fabaceae-faboideae) is a medicinal tree that is commonly used in brazil for the treatment of several central nervous system disorders.201222480245
characterization and pharmacological properties of a novel multifunctional kunitz inhibitor from erythrina velutina seeds.inhibitors of peptidases isolated from leguminous seeds have been studied for their pharmacological properties. the present study focused on purification, biochemical characterization and anti-inflammatory and anticoagulant evaluation of a novel kunitz trypsin inhibitor from erythrina velutina seeds (evti). trypsin inhibitors were purified by ammonium sulfate (30-60%), fractionation followed by trypsin-sepharose affinity chromatography and reversed-phase high performance liquid chromatography. t ...201323737945
the introduced tree prosopis juliflora is a serious threat to native species of the brazilian caatinga vegetation.despite its economic importance in the rural context, the prosopis juliflora tree species has already invaded millions of hectares globally (particularly rangelands), threatening native biodiversity and rural sustainability. here we examine seedling growth (leaf area, stem diameter, plant height) and seedling mortality across five native plant species of the caatinga vegetation in response to competition with p. juliflora. two sowing treatments with 10 replications were adopted within a factoria ...201424594739
populations of erythrina velutina willd. at risk of extinction.the goal of this study was to characterize the structure of two natural populations of the coral tree using rapd and issr markers. the study evaluated all individuals in two different areas in the northeastern region of brazil: the first was in the riparian area, 10 km x 100 m along the edge of the lower são francisco river, and the second was in the municipality of pinhão, in a semiarid region between the municipalities of neópolis and santana do são francisco. we used all the coral trees prese ...201526345968
making a bad situation worse: an invasive species altering the balance of interactions between local species.biological invasions pose a significant threat to biodiversity, especially on oceanic islands. one of the primary explanations for the success of plant invaders is direct suppression of competitors. however, indirect interactions can also be important, although they are often overlooked in studies on biological invasion. the shrub leucaena leucocephala is a widespread island invader with putative allelopathic effects on the germination and growth of other species. we quantified the impact of leu ...201627010846
a comparative framework of the erythrina velutina tree species in reforested land and native populations.erythrina velutina willd. (fabaceae: papillionoideae) is a pioneer species found in tropical and subtropical regions of the world that has medicinal properties and that is used in reforestation projects. this species is rare in some areas of northeastern brazil. this study aimed to characterize and compare genetic structures of natural and restored populations of e. velutina, with a focus on the selection of tree seeds. a total of 108 individuals from five natural populations and one restored po ...201627323200
homohesperetin and phaseollidin from erythrina velutina. 200111274777
antinociceptive activities of the hydroalcoholic extracts from erythrina velutina and erythrina mulungu in mice.this work studied the antinociceptive effects of the hydroalcoholic extracts (haes) from erythrina velutina (ev) and erythrina mulungu (em) in three experimental models of nociception in mice. the extract was administered intraperitoneally to female mice at the doses of 200 and 400 mg/kg. inhibitions of abdominal contractions were observed with the doses of 200 (88.6%; 86.8%) and 400 (95.5%; 83.5%) mg/kg of e. velutina and e. mulungu, respectively, as compared to controls. e. velutina and e. mul ...200312843615
central activity of hydroalcoholic extracts from erythrina velutina and erythrina mulungu in mice.this work studied the central behavioural effects of hydroalcoholic extracts from the stem bark of erythrina velutina and erythrina mulungu on the elevated plus maze, open field, and rota rod tests in mice. these medicinal plants belong to the fabaceae family and are popularly used in brazil for their effects on the central nervous system. single doses of the extracts were administered orally (200, 400 or 800 mg kg(-1)) or intraperitoneally (200 or 400 mg kg(-1)) to female mice. a reduction of t ...200415025865
effects of a chitin binding vicilin from erythrina velutina seeds on bean bruchid pests (callosobruchus maculatus and zabrotes subfasciatus).erythrina velutina vicilin, evv, is a dimeric glycoprotein with mr of 124.6 kda. evv was tested for anti-insect activity against bean bruchid larvae. evv had ld(50) of 0.10% and ed(50) of 0.14% for z. subfasciatus and ld(50) of 0.26% and ed(50) of 0.19% for c. maculatus. evv was not digested by bean larvae enzymes until 12 h of incubation, and at 24 h evv was more resistant to z. subfasciatus enzymes.200818336356
proteolytic digestive enzymes and peritrophic membranes during the development of plodia interpunctella (lepidoptera: piralidae): targets for the action of soybean trypsin inhibitor (sbti) and chitin-binding vicilin (evv).the digestive system of p. interpunctella was characterized during its larval development to determine possible targets for the action of proteinaceous enzyme inhibitors and chitin-binding proteins. high proteolytic activities using azocasein at ph 9.5 as substrate were found. these specific enzymatic activities (au/mg protein) showed an increase in the homogenate of third instar larvae, and when analyzed by individual larvae (au/gut), the increase was in sixth instar larvae. zymograms showed tw ...200818693741
trail-enhancing activity of erythrinan alkaloids from erythrina velutina.a new erythrinan alkaloid (1), erythodine n-oxide, was isolated from the seeds of erythrina velutina together with seven known erythrinan alkaloids (2-7, 9) and an indole alkaloid (8). the structure of new compound (1) was elucidated by spectroscopic methods. six of the nine compounds showed enhanced activity when combined with tumor necrosis factor-related apoptosis-inducing ligand (trail). erysotrine (4) did not show cytotoxic activity by itself, but exhibited significant cytotoxicity when com ...200919026536
erythrinan alkaloids from seeds of erythrina velutina.four new erythrinan alkaloids (1-4) were isolated from the seeds of erythrina velutina. the structures of these new compounds 1-4 were elucidated by spectroscopic methods including 2d-nmr. three of four were found to be novel sulfated erythrinan alkaloids.201121532193
water uptake mechanism and germination of erythrina velutina seeds treated with atmospheric plasma.the effect of plasma applied to mulungu (erythrina velutina) seeds was studied to verify its influence on the germination, water absorption, wettability and structure of the seeds. the plasma jet used in this study was produced by dielectric barrier discharge (dbd) in a helium gas flow of 0.03 l/s at a distance of 13 mm for 60 s. the plasma treatment significantly affected the seed germination rate, which was approximately 5% higher than that of the untreated group. micropyle and hilum contribut ...201627670654
pharmacognostical analysis and protective effect of standardized extract and rizonic acid from erythrina velutina against 6-hydroxydopamine-induced neurotoxicity in sh-sy5y cells.erythrina velutina is a tree common in the northeast of brazil extensively used by traditional medicine for the treatment of central nervous system disorders.201727867274
gastroprotective and antielastase effects of protein inhibitors from erythrina velutina seeds in an experimental ulcer model.trypsin and chymotrypsin inhibitors from erythrina velutina seeds have been previously isolated by our group. in previous studies using a sepsis model, we demonstrated the antitumor and anti-inflammatory action of these compounds. this study aimed to evaluate the gastroprotective and antielastase effects of protein inhibitors from e. velutina seeds in an experimental stress-induced ulcer model. two protein isolates from e. velutina seeds, with antitrypsin (piat) and antichymotrypsin (piaq) activ ...201728177773
larvicidal effects of a chitin-binding vicilin from erythrina velutina seeds on the mediterranean fruit fly ceratitis capitata.chitin-binding vicilin from erythrina velutina seeds was purified by ammonium sulfate followed by affinity chromatography on a chitin column and gel filtration on superose-6-10-300-gl. the erythrina velutina vicilin, called evv, is a tetrameric glycoprotein composed of 1.85% carbohydrates and m r of 216.6 kda, consisting of two subunits of m r of 54.8 and two subunits of m r of 50.8 kda. the evv homogeneity was confirmed in native page where it was observed to be a unique acid-protein band with ...200818193829
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