| newer applications of the histological stain prepared from pterocarpus santalinus. | a histological stain prepared from the heartwood of pterocarpus santalinus linn. has been found to be an excellent nuclear stain for various cells of animal and plant origin. as an elastic tissue stain, the results are comparable to standard elastic tissue stains. the striations of voluntary muscle fibers are well shown. the nissl granules and fibers of cranial nerves in the pons are visualized. when counterstained with light green, it differentially stains muscle and fibrous tissue. the stain c ... | 1981 | 6166099 |
| effect of oral administration of bark extracts of pterocarpus santalinus l. on blood glucose level in experimental animals. | the effect of administration of different doses of pterocarpus santalinus l. bark extracts in normal and diabetic rats, on blood glucose levels was evaluated in this study. among the three fractions (aqueous, ethanol and hexane), ethanolic fraction at the dose of 0.25 g/kg body weight showed maximum antihyperglycemic activity. the same dose did not cause any hypoglycemic activity in normal rats. the results were compared with the diabetic rats treated with glibenclamide and the antihyperglycemic ... | 2001 | 11137350 |
| wound healing potential of pterocarpus santalinus linn: a pharmacological evaluation. | the need for new therapeutics for wound healing has encouraged the drive to examine the nature and value of plant products. ayurveda, the indian traditional system of medicine, mentions the values of medicinal plants for wound healing. one of these is pterocarpus santalinus. this article describes a pharmacological study to evaluate its toxicity as well as wound-healing potential in animal studies. powder made from the wood of the p. santalinus tree was used to make up an ointment in a petroleum ... | 2004 | 15866805 |
| plant medicines of indian origin for wound healing activity: a review. | research on wound healing drugs is a developing area in modern biomedical sciences. scientists who are trying to develop newer drugs from natural resources are looking toward the ayurveda, the indian traditional system of medicine. several drugs of plant, mineral, and animal origin are described in the ayurveda for their wound healing properties under the term vranaropaka. most of these drugs are derived from plant origin. some of these plants have been screened scientifically for the evaluation ... | 2003 | 15866825 |
| pterocarpus santalinus: a traditional herbal drug as a protectant against ibuprofen induced gastric ulcers. | the ethanol extract of pterocarpus santalinus (ps) was evaluated for gastroprotection in rats using ibuprofen as the induction model. rats treated with ps (100-400 mg/kg) showed a significant reduction in gastric lesions. ps at a dose of 200 mg/kg was found to be the minimum effective dose and hence further studies with that dose were carried out. ps treatment increased the ldh activity and decreased the lipid peroxidation levels. the extract had the ability to increase the antioxidant enzymes s ... | 2005 | 16317653 |
| methanolic extract of pterocarpus santalinus induces apoptosis in hela cells. | ptercarpus santalinus (fabaceae) has been used as a folk remedy in korea, and it has been shown to exhibit antiinflammations, antiulcers and anticancer effects. in this study, therefore, we report the cytotoxic activity and the mechanism of cell death exhibited by the methanol extract of ptercarpus santalinus (meps) against human cervical adenocarcinoma cell line, hela. treatment of hela cells with various concentrations of meps resulted in growth inhibition and induction of apoptosis in a dose- ... | 2006 | 16326057 |
| pterocarpus santalinus: an in vitro study on its anti-helicobacter pylori effect. | the anti-h. pylori activity of pterocarpus santalinus (ps), a traditional herb, has been assessed and compared with that of bismuth subcitrate, through in vitro studies employing rat gastric epithelial cell cultures and h. pylori isolates from gastric mucosal biopsy patients. the mic of ps was found to be 20 microg/ml. h. pylori was co-cultivated with rat gastric epithelial cells in the presence/absence of ps at its mic. a reduction in the activity of urease, a normal appearance of the epithelia ... | 2007 | 17128431 |
| role of pterocarpus santalinus against mitochondrial dysfunction and membrane lipid changes induced by ulcerogens in rat gastric mucosa. | free radicals produced by ulcerogenic agents affect the tca cycle enzymes located in the outer membrane of the mitochondria. upon induction with ulcerogens, peroxidation of membrane lipids bring about alterations in the mitochondrial enzyme activity. this indicates an increase in the permeability levels of the mitochondrial membrane. the ability of pse to scavenge the reactive oxygen species results in restoration of activities of tca cycle enzymes. nsaids interfere with the mitochondrial beta-o ... | 2007 | 17719569 |
| effect of pterocarpus santalinus bark, on blood glucose, serum lipids, plasma insulin and hepatic carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats. | the present study was designed to investigate the effect of bark of pterocarpus santalinus, an ethnomedicinal plant, on blood glucose, plasma insulin, serum lipids and the activities of hepatic glucose metabolizing enzymes in streptozotocin-induced diabetic rats. | 2010 | 20178824 |
| anti-inflammatory and cytotoxic neoflavonoids and benzofurans from pterocarpus santalinus. | five new benzofurans, pterolinuses a-e (1-5), six new neoflavonoids, pterolinuses f-j (8-13), and five known compounds (6, 7, 14-16) were isolated from an extract of pterocarpus santalinus heartwood. all new structures were elucidated by spectroscopic methods, and configurations were confirmed by cd spectral data and optical rotation values. the isolates were evaluated for anti-inflammatory and cytotoxic activities. six compounds (1, 2, 4, 6, 7, and 15) showed significant inhibition in at least ... | 2011 | 21488654 |
| bioactive components from the heartwood of pterocarpus santalinus. | one new phenanthrenedione, pterolinus k (1), and one new chalcone, pterolinus l (2) were isolated from the heartwood extract of pterocarpus santalinus. the structures were elucidated by spectroscopic methods. both 1 and 2 showed inhibitory effect on elastase release by human neutrophils in response to fmlp with an ic(50) value of 4.24 and 0.95µm, and compound 1 also inhibited superoxide anion generation with ic(50) value of 0.99µm. in addition, compound 1 showed selective cytotoxicity against he ... | 2011 | 21784631 |
| in vitro antibacterial efficacy of 21 indian timber-yielding plants against multidrug-resistant bacteria causing urinary tract infection. | to screen methanolic leaf extracts of 21 timber-yielding plants for antibacterial activity against nine species of uropathogenic bacteria isolated from clinical samples of a hospital (enterococcus faecalis, staphylococcus aureus, acinetobacter baumannii, citrobacter freundii, enterobacter aerogenes, escherichia coli, klebsiella pneumoniae, proteus mirabilis, and pseudomonas aeruginosa). | 2013 | 24524024 |
| quorum quenching activity in cell-free lysate of endophytic bacteria isolated from pterocarpus santalinus linn., and its effect on quorum sensing regulated biofilm in pseudomonas aeruginosa pao1. | quorum sensing mechanism allows the microorganisms to resist the antibiotic treatment by forming biofilms. quorum quenching is one of the mechanisms to control the development of drug resistance in microbes. endophyte bacteria are beneficial to plant growth as they support the immune system against the pathogen attack. the endophytic bacteria present in pterocarpus santalinus were screened for the presence of n-acyl homoserine lactones (ahls) degrading bacteria using biosensor strains and furthe ... | 2014 | 24268182 |
| natural product htp screening for attenuation of cytokine-induced neutrophil chemo attractants (cincs) and no2- in lps/ifnγ activated glioma cells. | chronic and acute central nervous system (cns) inflammation are contributors toward neurological injury associated with head trauma, stroke, infection, parkinsons or alzheimers disease. cns inflammatory illnesses can also contribute toward risk of developing glioblastoma multiforme (gbm). with growing public interest in complementary and alternative medicines (cams), we conduct a high throughput (htp) screening of >1400 natural herbs, plants and over the counter (otc) products for anti-inflammat ... | 2017 | 27956075 |