toxicological profile of medically relevant crotalus species from mexico and their neutralization by a crotalus basiliscus/bothrops asper antivenom. | specimens of the crotalus genus represent a potential snakebite problem in mexico, and despite the great number of species of crotalus present in this country, only a few of them are relevant from a medical point of view. crotalus envenomed patients can present a range of signs and symptoms, depending on the species involved, and their treatment is indistinctly with either of the anti-viperid antivenoms available in the mexican public health system. one of these antivenoms is produced by immuniz ... | 2020 | 32345455 |
integrated venomics and venom gland transcriptome analysis of juvenile and adult mexican rattlesnakes crotalus simus, c. tzabcan, and c. culminatus revealed mirna-modulated ontogenetic shifts. | adult rattlesnakes within genus crotalus express one of two distinct venom phenotypes, type i (hemorrhagic) and type ii (neurotoxic). in costa rican central american rattlesnake, ontogenetic changes in the concentration of mirnas modulate venom type ii to type i transition. venomics and venom gland transcriptome analyses showed that adult c. simus and c. tzabcan expressed intermediate patterns between type ii and type i venoms, whereas c. culminatus had a canonical type i venom. neonate/juvenile ... | 2017 | 28731347 |