| [hplc determination of uracil xanthine, hypoxanthine and uridine in species of animal drugs]. | to make further studies on the water-soluble components in animal drugs by determining the contents of uracil, xanthine, hypoxanthine and uridine from ten species of animal drugs. | 1999 | 12242810 |
| bioactive compounds from the insect aspongopus chinensis. | recent studies focusing on unveiling the biological agents of aspongopus chinensis have led to the identification of four new norepinephrine derivatives (1-4), three new sesquiterpenoids (5-7), and one new lactam (8). in addition, twenty-three known compounds have been identified, most of which were isolated from this insect for the first time. selected members of insect-derived substances were evaluated for their biological activities against renal protection in high-glucose-induced mesangial c ... | 2014 | 25442305 |
| (±)-aspongamide a, an n-acetyldopamine trimer isolated from the insect aspongopus chinensis, is an inhibitor of p-smad3. | (±)-aspongamide a (1), an unusual trimer of n-acetyldopamine (nada) bearing a novel tetrahydrobenzo[a]dibenzo[b,e][1,4]dioxine structure, and a pair of nada dimeric enantiomers (2) were isolated from aspongopus chinensis. the structures of compounds 1 and 2 were assigned using spectroscopic methods. compound 1 was found to be an inhibitor of smad3 phosphorylation in transforming growth factor-β1 (tgf-β1) induced rat renal proximal tubular cells and suppressed extracellular matrix expression in m ... | 2014 | 24383883 |
| on the structure of aspongopusin recently isolated from aspongopus chinensis. | the 2,5-disubstituted oxazole recently proposed for aspongopusin, a natural product isolated from aspongopus chinensis, was synthesized through an unambiguous route. the synthetic sample showed (1)h and (13)c nmr entirely different from those in the literature, revealing that the initially assigned structure was incorrect. the spectroscopic data for the given structure are thus made available for the first time. | 2013 | 23266734 |
| the biosynthetic products of chinese insect medicine, aspongopus chinensis. | a new oxazole (1) was obtained from chinese insect medicine aspongopus chinensis, along with three known n-acetyldopamine derivatives (2-4). their structures were determined on the basis of nmr and esi-ms analyses. the possible biosynthetic pathways of the isolated compounds are discussed. cytotoxicities of those compounds against 10 selected cancer cells were measured in vitro. | 2012 | 22430116 |