| screening of congenital cytomegalovirus infection by real-time pcr in urine pools. | human cytomegalovirus (hcmv) is the most frequent cause of congenital infection. despite the fact that 5-17% of asymptomatic infected babies will develop late sequelae and, therefore, should be closely followed, most of these children will remain undetected, as screening of all newborns by viral culture is too expensive and no valid alternative has been widely accepted. the aim of this work was to demonstrate that pool testing can be used to screen hcmv congenital infection in newborns. for this ... | 2011 | 21614511 |
| molecular diversity assessed by vntr and is1296 typing of historical mycoplasma mycoides subsp. mycoides sc strains. | the last case of contagious bovine pleuropneumonia (cbpp), caused by mycoplasma mycoides subsp. mycoides sc (mmmsc), in europe was reported in portugal in 1999. however, in view of its insidious nature, it is still possible that cbpp could re-emerge. despite differences in animal host and geographical origin, most of the european mmmsc field isolates were traditionally considered to be very homogeneous. in the present study we performed a retrospective variable-number tandem repeat (vntr) and is ... | 2010 | 20542647 |
| assessment of biological effects of pollutants in a hyper eutrophic tropical water body, lake beira, sri lanka using multiple biomarker responses of resident fish, nile tilapia (oreochromis niloticus). | biomarkers measured at the molecular and cellular level in fish have been proposed as sensitive "early warning" tools for biological effect measurements in environmental quality assessments. lake beira is a hypertrophic urban water body with a complex mixture of pollutants including polycyclic aromatic hydrocarbons (pahs) and microcystins. in this study, a suite of biomarker responses viz. biliary fluorescent aromatic compounds (facs), hepatic ethoxyresorufin o-deethylase (erod) and glutathione ... | 2010 | 20229025 |
| doppel gene polymorphisms in portuguese sheep breeds: insights on ram fertility. | transgenic knockout of the gene encoding the prion-like protein doppel leads to male infertility in mice. the precise role of doppel in male fertility is still unclear, but sperm from doppel-deficient mice appear to be unable to undergo the normal acrosome reaction necessary to penetrate the zona pellucida of the oocyte. the objective of this study was to characterize doppel (prnd) gene polymorphisms in eight portuguese sheep breeds and to determine a possible relationship between these polymorp ... | 2009 | 19028030 |
| characteristics of a pandemic clone of o3 : k6 and o4 : k68 vibrio parahaemolyticus isolated in beira, mozambique. | the genetic characteristics of vibrio parahaemolyticus strains isolated in 2004 and 2005 in mozambique were assessed in this study to determine whether the pandemic clone of v. parahaemolyticus o3 : k6 and o4 : k68 serotypes has spread to mozambique. fifty-eight v. parahaemolyticus strains isolated from hospitalized diarrhoea patients in beira, mozambique, were serotyped for o : k antigens and genotyped for toxr, tdh and trh genes. a group-specific pcr, a pcr that detects the presence of orf8 of ... | 2008 | 19018020 |
| cutaneous disorders in the "bairro inhamudima" of beira, mozambique. | there are no reliable data on the prevalence of skin diseases in mozambique. | 2007 | 17958629 |
| validation of an electrothermal atomization atomic absorption spectrometry method for quantification of total chromium and chromium(vi) in wild mushrooms and underlying soils. | an etaas method was validated to quantify total cr and cr(vi) in mushrooms and the underlying soils. the method includes a sample pretreatment for total cr dissolution using a wet acid digestion procedure and a selective alkaline extraction for cr(vi). the limits of detection were, expressed in microg/l, 0.15 and 0.17 for total cr and cr(vi), respectively. the linearity ranges under the optimized conditions were 0.15-25.0 and 0.17-20.0 microg/l for total cr and cr(vi), respectively. the limits o ... | 2007 | 17661487 |
| modeling hiv transmission risk among mozambicans prior to their initiating highly active antiretroviral therapy. | understanding sexual behavior and assessing transmission risk among people living with hiv-1 is crucial for effective hiv-1 prevention. we describe sexual behavior among hiv-positive persons initiating highly active antiretroviral therapy (haart) in beira, mozambique. we present a bernoulli process model (tool available online) to estimate the number of sexual partners who would acquire hiv-1 as a consequence of sexual contact with study participants within the prior three months. baseline data ... | 2007 | 17505919 |
| using nurses to identify haart eligible patients in the republic of mozambique: results of a time series analysis. | the most pressing challenge to achieving universal access to highly active anti-retroviral therapy (haart) in sub-saharan africa is the shortage of trained personnel to handle the increased service requirements of rapid roll-out. overcoming the human resource challenge requires developing innovative models of care provision that improve efficiency of service delivery and rationalize use of limited resources. | 2007 | 17328804 |
| genetic characterization of human immunodeficiency virus type 1 from beira, mozambique. | in this report, we examined the genetic diversity of hiv-1 strains circulating in the city of beira, the second largest metropolitan area in mozambique. a total of 131 blood samples, collected between august and october 2003 from antiretroviral-naïve individuals, were characterized with a combined approach consisting of heteroduplex mobility assay (hma) subtyping for gag (n=74) and/or env (n=117) genes, and dna sequence analysis of proviral env (c2v3c3, n=52), ltr (n=30) and/or pol (n=43) genomi ... | 2006 | 16849040 |
| is hiv infection associated with an increased risk for cholera? findings from a case-control study in mozambique. | as residents of sub-saharan africa are at high risk for hiv and cholera, it is biologically plausible that immune suppression caused by hiv infection predisposes to cholera. our aim was to assess the potential association between both diseases. | 2008 | 18331384 |
| aeroallergens sensitization in an allergic paediatric population of cova da beira, portugal. | cova da beira is an interior central region of portugal, with a population of 93,000 inhabitants. the first pollen counts performed in portugal revealed the highest values of the country in this area. the aim of this study was to assess the aeroallergens sensitization in an allergic population, according to the age groups. in a 5 year period (1995-2000) 1790 consecutive outpatients were observed for suspected allergic symptoms. we included in this study all the 557 paediatric (< or = 15 years ol ... | 2005 | 16045856 |
| diagnosis of congenital cytomegalovirus infection by detection of viral dna in urine pools. | human cytomegalovirus (hcmv) is the most frequent cause of congenital infection. diagnosis of this infection is important because 5-17% of asymptomatic infected babies will develop late sequelae and should be followed closely. most of these children will remain undetected, since screening of all newborns by viral culture is too expensive. the aim of this study was to demonstrate that pool testing could be used to detect hcmv congenital infection in newborns. for this purpose, a nested-pcr techni ... | 2005 | 16023520 |
| urban versus rural environment--any differences in aeroallergens sensitization in an allergic population of cova da beira, portugal? | cova da beira is an interior central region of portugal, with a population of 93000 inhabitants divided in urban and rural living areas. the aim of this study was to access the prevalence of aeroallergens sensitisation in an allergic population, according to the urban and the rural environmental exposure and according to age. 1096 patients observed for suspected allergic symptoms, for a five-year period (1995-2000) were submitted to skin prick tests and were included in this study. they were div ... | 2005 | 15984318 |
| pandemic serovars (o3:k6 and o4:k68) of vibrio parahaemolyticus associated with diarrhea in mozambique: spread of the pandemic into the african continent. | forty-two episodes of vibrio parahaemolyticus infections were detected in beira, mozambique, from january to may 2004. the majority of the isolates (81%) belonged to the pandemic serovars (o3:k6 and o4:k68) of v. parahaemolyticus. the pandemic serovars were positive by group-specific pcr (gs-pcr) and a pcr specific for open reading frame orf8 (orf8-pcr), which are molecular markers of the pandemic clone, and were positive for tdh but negative for trh. the remaining 19% of the strains also posses ... | 2005 | 15956363 |
| effectiveness of mass oral cholera vaccination in beira, mozambique. | new-generation, orally administered cholera vaccines offer the promise of improved control of cholera in sub-saharan africa. however, the high prevalence of human immunodeficiency virus (hiv) infection in many cholera-affected african populations has raised doubts about the level of protection possible with vaccination. we evaluated a mass immunization program with recombinant cholera-toxin b subunit, killed whole-cell (rbs-wc) oral cholera vaccine in beira, mozambique, a city where the seroprev ... | 2005 | 15728808 |
| [aids: is it a risk factor in cerebrovascular disease?]. | cerebrovascular disease (cvd) has become an important health problem throughout the world. it is generally one the main causes of morbidity and mortality in the world, especially in developed countries. in these countries the frequency with which it appears is linked with the progress reached in the organisation of the public health system and the higher economic and social standards of their populations, which have given rise to prolonged life expectancy and a greater number of elderly people. ... | 2002 | 12436376 |
| ecology of sand flies (diptera: psychodidae: phlebotominae) in the north of the state of mato grosso, brazil. | peixoto de azevedo is located in the north of state of mato grosso, where environmental alterations led to an outbreak of american cutaneous leishmaniasis in the 80s. the parasite from patients was characterized as leishmania (v.) braziliensis. the aim of this study is to contribute to the sand fly ecology of central-west brazil. captures were carried out monthly using cdc light traps. twenty-six species of sand fly were characterized; among which lutzomyia (lutzomyia) spathotrichia, l. runoides ... | 2002 | 12118273 |
| barriers to access to antiretroviral treatment in mozambique, as perceived by patients and health workers in urban and rural settings. | this study identifies, ranks, and compares factors perceived as barriers to accessing antiretroviral treatment (art) in urban and rural settings in mozambique. data were collected between march and july 2008. it consisted of 13 focus group discussions and a structured questionnaire administered to 252 people living with hiv/aids (plwha) and 28 health workers in the districts of beira and buzi. data analysis was performed using content analysis, factor analysis, and percentages of the maximum att ... | 2009 | 19803678 |
| microbiology and biochemistry of cheeses with appélation d'origine protegée and manufactured in the iberian peninsula from ovine and caprine milks. | to support legal protection with objective technical data and to promote enforcement of high quality standards a few european countries have created appélation d'origine protegées. this paper reviews and updates fundamental and applied aspects encompassing microbiological and biochemical characteristics of traditional cheeses with appélation d'origine protegée manufactured in the iberian peninsula from ovine, caprine, or both milks. ovine and caprine cheeses with appélation d'origine protegée fr ... | 2000 | 10750117 |
| syphilis in pregnant women in mozambique. | to establish the prevalence of syphilis in pregnant women in mozambique and evaluate present diagnostic methods, 1468 pregnant women in eight of the country's 10 provinces were examined using the venereal disease research laboratory (vdrl) test. positive serum samples were also analysed using the treponema pallidum haemagglutination (tpha) assay and one group was also analysed using the fluorescent treponemal antibody absorbed (fta-abs) test. the prevalence of vdrl seroreactivity was found to be ... | 1985 | 3910543 |
| effects of immigration on the prevalence of malaria in rural areas of the amazon basin of brazil. | epidemiological studies were conducted on malaria in three rural areas of the amazon basin in the state of rondônia: the town of costa marques, forte principe da beira (fort), and an immigrant settlement in the nearby forest. these studies were instituted to document the malaria problem and to describe the role of immigration on its distribution and prevalence. hospital records in the town show that the number of malaria cases increased five fold from 1983 to 1987 and that the predominant malari ... | 1989 | 2487445 |
| age-specific mortality patterns in central mozambique during and after the end of the civil war. | abstract: background: in recent years, vigorous debate has developed concerning how conflicts contribute to the spread of infectious diseases, and in particular, the role of post-conflict situations in the epidemiology of hiv/aids. this study details the age-specific mortality patterns among the population in the central provincial capital of beira, mozambique, during and after the mozambican civil war which ended in 1992. methods: data was collected from the death register at beira's central ho ... | 2011 | 21615947 |
| field evaluation of a rapid immunochromatographic dipstick test for the diagnosis of cholera in a high-risk population. | early detection of cholera outbreaks is crucial for the implementation of the most appropriate control strategies. | 2006 | 16451731 |
| modified directly observed therapy to facilitate highly active antiretroviral therapy adherence in beira, mozambique. development and implementation. | as resource-limited countries expand access to highly active antiretroviral therapy (haart) treatment, innovative programs are needed to support adherence in the context of significant health system barriers. modified directly observed therapy (mdot) is one such strategy, but little is known about the process of designing and implementing mdot programs for haart in resource-limited settings. in this descriptive study, we used a mixed-methods approach to describe the process of implementing mdot ... | 2006 | 17133197 |
| the photoreceptor cell-specific nuclear receptor gene (pnr) accounts for retinitis pigmentosa in the crypto-jews from portugal (marranos), survivors from the spanish inquisition. | the last crypto-jews (marranos) are the survivors of spanish jews who were persecuted in the late fifteenth century, escaped to portugal and were forced to convert to save their lives. isolated groups still exist in mountainous areas such as belmonte in the beira-baixa province of portugal. we report here the genetic study of a highly consanguineous endogamic population of crypto-jews of belmonte affected with autosomal recessive retinitis pigmentosa (rp). a genome-wide search for homozygosity a ... | 2000 | 11071390 |
| predictors of treatment failure in hiv-positive children receiving combination antiretroviral therapy: cohort data from mozambique and uganda. | delays detecting treatment failure and switching to second-line combination antiretroviral therapy (cart) are often observed in human immunodeficiency virus (hiv)-infected children of low-middle-income countries (lmic). | 2015 | 26407356 |
| blood values of captive beira antelope (dorcatragus megalotis) prior to and during an outbreak of fibrinous pleuropneumonia syndrome (fpps). | currently the only captive population of beira antelope (dorcatragus megalotis) is held at the al wabra wildlife preservation, qatar. an outbreak of a severe respiratory disease--fibrinous pleuropneumonia syndrome, most likely caused by mycoplasma ovipneumoniae--led to a marked population decline. reactive systemic inflammatory (aa) amyloidosis was noted as a chronic manifestation of the disease. blood samples had been collected for biochemistry and hematology baseline values prior to the outbre ... | 2014 | 25632657 |
| extremely high prevalence of multi-resistance among uropathogens from hospitalised children in beira, mozambique. | a prospective surveillance study was conducted to investigate the epidemiology and patterns of antibiotic resistance among uropathogens from hospitalised children in beira, mozambique. additionally, information regarding determinants of a urinary tract infection (uti) was obtained. | 2013 | 23725956 |
| kaposi sarcoma incidence in mozambique: national and regional estimates. | kaposi sarcoma is expressed in four clinical variants, all associated with human herpes virus type 8 infection, namely, classic, endemic, immunosuppression-related and aids-related. the latter currently accounts for most of the burden of kaposi sarcoma in sub-saharan africa, reflecting the frequency of hiv infection and its management. we aimed to estimate the incidence of kaposi sarcoma in mozambique and in its provinces. we estimated the number of incident cases of kaposi sarcoma by adding up ... | 2015 | 25494288 |
| mycobacterium tuberculosis resistance to antituberculosis drugs in mozambique. | to determine the drug resistance profile of mycobacterium tuberculosis in mozambique. | 2017 | 24831398 |
| diagnosing polyparasitism in a high-prevalence setting in beira, mozambique: detection of intestinal parasites in fecal samples by microscopy and real-time pcr. | many different intestinal parasite species can co-occur in the same population. however, classic diagnostic tools can only frame a particular group of intestinal parasite species. hence, one or two tests do not suffice to provide a complete picture of infecting parasite species in a given population. the present study investigated intestinal parasitic infections in beira, mozambique, i.e. in the informal settlement of inhamudima. diagnostic accuracy of five classical microscopy techniques and re ... | 2017 | 28114314 |
| emergence of methicillin resistance and panton-valentine leukocidin positivity in hospital- and community-acquired staphylococcus aureus infections in beira, mozambique. | the objective of this study was to investigate the antibiotic resistance patterns, including methicillin resistance, inducible macrolide-lincosamide-streptogramin b (mlsb ) resistance and panton-valentine leukocidin (pvl) toxin gene carriage among hospital-acquired staphylococcus aureus (ha-sa) and community-acquired s. aureus (ca-sa), in beira, mozambique. | 2014 | 24205917 |
| simple motor tasks independently predict extubation failure in critically ill neurological patients. | to evaluate the usefulness of simple motor tasks such as hand grasping and tongue protrusion as predictors of extubation failure in critically ill neurological patients. | 2017 | 28746528 |
| soap methodology in general practice/family medicine teaching in practical context. | medical records in general practice/family medicine are an essential information support on the health status of the patient and a communication document between health professionals. the development of competencies in general practice/family medicine during pre-graduation must include the ability to make adequate medical records in practical context. as of 2012, medicine students at the university of beira interior have been performing visits using the subjective, objective, assessment and plan ... | 2016 | 28425889 |
| bisexual and bidirectional: assessing the potential for hiv bridging in mozambique. | african men who have sex with men (msm) frequently, and often concurrently, have female partners, raising concerns about hiv sexual bridging. we explored potential hiv transmission in mozambique from and to female partners of msm focusing on preferred anal sex role and circumcision status. data collected in a respondent-driven sampling study of msm in 2011 in maputo and beira. men who had oral or anal sex with other men 12 months prior completed a questionnaire and consented for hiv testing. sta ... | 2017 | 29188391 |
| prevalence of diabetes mellitus in newly diagnosed pulmonary tuberculosis in beira, mozambique. | data regarding the association between diabetes mellitus (dm) and tuberculosis (tb) in africa are scarce. dm screening among tb patients in mozambique was carried out. | 2017 | 29085405 |
| developing nurse medication safety training in a health partnership in mozambique using behavioural science. | globally, safe and effective medication administration relies on nurses being able to apply strong drug calculation skills in their real-life practice, in the face of stressors and distractions. these may be especially prevalent for nurses in low-income countries such as mozambique and continuing professional development post-registration may be important. this study aimed to 1) explore the initial impact of an international health partnership's work to develop a drug calculation workshop for nu ... | 2017 | 28676121 |
| multi-site cholera surveillance within the african cholera surveillance network shows endemicity in mozambique, 2011-2015. | mozambique suffers recurrent annual cholera outbreaks especially during the rainy season between october to march. the african cholera surveillance network (africhol) was implemented in mozambique in 2011 to generate accurate detailed surveillance data to support appropriate interventions for cholera control and prevention in the country. | 2017 | 28991895 |
| simulation in medical school education. | the universidade da beira interior (ubi), covilhã, portugal in the medical degree course uses simulation in an integrated and comprehensive program as a pedagogical tool. | 2017 | 28873924 |
| a cross-sectional serological study of cysticercosis, schistosomiasis, toxocariasis and echinococcosis in hiv-1 infected people in beira, mozambique. | helminthic infections are highly endemic in mozambique, due to limited access to healthcare and resources for disease prevention. data on the subclinical prevalence of these diseases are scarce due to the fact that an immunological and imaging diagnosis is not often available in endemic areas. we conducted a cross-sectional study on hiv1(+) patients from beira city in order to determine the seroprevalence of cysticercosis, schistosomiasis, toxocariasis and echinoccocosis and its possible interac ... | 2014 | 25188395 |
| seroprevalence of toxoplasma gondii in dogs of riverside communities of mato grosso pantanal, brazil. | toxoplasma gondii is an intracellular protozoan with worldwide distribution and dogs act as sentinels of human infection. this search aimed to determine the occurrence of antibodies against t. gondii in dogs of the communities on the cuiabá river, mato grosso and variables associated with infection. the dogs of the riverside communities in cuiabá river, which includes barranco alto, praia do poço, engenho velho, varginha, bom sucesso, passagem da conceição and são gonçalo beira rio, were evaluat ... | 2016 | 27925062 |
| high burden of hiv infection and risk behaviors among female sex workers in three main urban areas of mozambique. | this is the first integrated biological and behavioral survey among female sex workers (fsw) in mozambique. using respondent-driven sampling, 400, 411 and 429 fsw were enrolled respectively in maputo, beira and nampula in 2011-2012. estimates were produced using rdsat 7.1. hiv prevalence was 31.2, 23.6, and 17.8 % in each location respectively. among hiv-positive fsw, 48.1, 79.8 and 89.6 % in each city, were unaware of their serostatus. condom use at last sex with a client was 85.8, 73.4 and 62. ... | 2016 | 26238035 |
| iodine deficiency and thyroid nodular pathology--epidemiological and cancer characteristics in different populations: portugal and south africa. | the prevalence and pathology pattern of iodine deficiency (id) related disorders are influenced by the dietary iodine intake: low iodine leads to thyroid nodular enlargement, to an increase in the incidence of thyroid cancer, an increase in anaplastic carcinomas and to an alteration in the papillary to follicular neoplasia ratio. this study aims at highlighting the effects of id by comparatively evaluating the pattern of thyroid nodular pathology in different populations that, although geographi ... | 2015 | 26126625 |
| drug-resistant tuberculosis in central mozambique: the role of a rapid genotypic susceptibility testing. | genotypic molecular testing may be very helpful for tuberculosis (tb) drug-resistance surveillance and for treatment guidance in low resource settings. | 2016 | 27534745 |
| detection of katg and inha mutations to guide isoniazid and ethionamide use for drug-resistant tuberculosis. | depending on the presence of mutations that determine isoniazid (inh) susceptibility (katg and inha), mycobacterium tuberculosis may be susceptible to high doses of inh or ethionamide (eth). | 2016 | 27393546 |
| genetic diversity of mycobacterium tuberculosis isolates obtained from patients with pulmonary tuberculosis in beira city, mozambique. | tuberculosis (tb) represents a serious public health problem in mozambique, with an estimated incidence rate of 548 cases per 100,000 population in 2011. information on the molecular epidemiology of mycobacterium tuberculosis (mtb) strains circulating in mozambique is limited. this study provides the first description of the genetic diversity of mtb strains circulating in beira city, the second largest town in mozambique. | 2014 | 26786330 |
| socio-demographic, marital, and psychosocial factors associated with condom use negotiation self-efficacy among mozambican women at risk for hiv infection. | in mozambique, women are the most affected by hiv/aids. self-efficacy is one of the main predictors of effective use of a condom. therefore, it is essential to identify the factors that influence condom-use negotiation self-efficacy in vulnerable women. the aim of this paper is to identify socio-demographic, marital, and psychosocial factors associated with condom-use negotiation self-efficacy among mozambican women at risk for hiv infection. | 2017 | 28831688 |
| reduced neonatal mortality in a regional hospital in mozambique linked to a quality improvement intervention. | neonatal mortality remains a serious health issue especially in low resource countries, where 99% of neonatal deaths occur. doctors with africa cuamm is an italian non-governmental organization in the field of healthcare that has been working in africa since 1955. in mozambique, at the central beira hospital (cbh), it has a project with the aim of supporting the neonatal intensive care unit (nicu) and the obstetrical department of the cbh through a multi-level intervention. our aim was to evalua ... | 2016 | 27876013 |
| incidence of endemic burkitt lymphoma in three regions of mozambique. | data on the burden and incidence of endemic burkitt lymphoma (ebl) across mozambique are scarce. we retrospectively retrieved information on ebl cases from reports of the three main hospitals of mozambique: maputo central hospital (mch), beira central hospital (bch), and nampula central hospital (nch) between 2004 and 2014. for 2015, we prospectively collected information of new ebl cases attending these hospitals. a total of 512 ebl cases were reported between 2004 and 2015: 153 ebl cases were ... | 2016 | 27799648 |
| iodine deficiency a persisting problem: assessment of iodine nutrition and evaluation of thyroid nodular pathology in portugal. | the goal of eliminating iodine deficiency (id) by the year 2000 has still not been achieved in several countries. more than 2 billion people worldwide (over 260 million school age children) remain id. in europe, there are still countries, such as portugal, without national general population data on iodine nutrition (in). this study aims at evaluating combined complementary data of the in of the general population through urinary iodine concentration (uic) and the thyroid histology profile from ... | 2017 | 27619914 |
| diagnosis, clinical presentation, and in-hospital mortality of severe malaria in hiv-coinfected children and adults in mozambique. | severe falciparum malaria with human immunodeficiency virus (hiv) coinfection is common in settings with a high prevalence of both diseases, but there is little information on whether hiv affects the clinical presentation and outcome of severe malaria. | 2012 | 22752514 |
| hiv incidence in a cohort of women at higher risk in beira, mozambique: prospective study 2009-2012. | hiv is prevalent in sofala province, mozambique. to inform future prevention research, we undertook a study in the provincial capital (beira) to measure hiv incidence in women at higher risk of hiv and assess the feasibility of recruiting and retaining them as research participants. | 2014 | 24475035 |
| prevalence, incidence and determinants of herpes simplex virus type 2 infection among hiv-seronegative women at high-risk of hiv infection: a prospective study in beira, mozambique. | to estimate the prevalence, incidence and determinants of herpes simplex type 2 (hsv-2) infection, and associations between hsv-2 and incident hiv infection, among women at higher risk for hiv infection in beira, mozambique. | 2014 | 24586973 |
| transmission of nevirapine-resistant hiv type 1 via breast milk to infants after single-dose nevirapine in beira, mozambique. | acquisition of nevirapine (nvp)-resistant human immunodeficiency virus type 1 (hiv-1) by breast-feeding infants after receipt of single-dose nvp to prevent mother-to-child transmission is not well defined. a prospective observational study of 307 infants evaluated the rate of breast milk transmission of nvp-resistant hiv and the concentrations of mutants over time. nvp resistance was detected in 9 of 24 infants (37.5%; 95% confidence interval, 18.8%-59.4%) infected via breast milk. eight had a p ... | 2014 | 24596282 |
| [anxiety in clinical settings: constructing a scale for medical students]. | the scale of anxiety in clinical setting (sacs) was constructed to assess the level of anxiety of medical students when exposed to the clinical setting and also to identify what situations are more likely to trigger higher levels of anxiety in that context. | 2016 | 25641288 |
| chronic utilization of agents acting on the renin-angiotensin system and intraoperative arterial pressure. | there has been concern that taking agents acting on the renin-angiotensin system (aras) in surgery day, may predispose patients to higher risk of intraoperative hypotension during surgery. therefore, the european society of cardiology and the european society of anesthesiology recommend transient discontinuation of aras before non-cardiac surgery in hypertensive patients. as the existent evidence is limited, this recommendation remains debated. | 2013 | 23467942 |
| the castanea sativa bur as a new potential ingredient for nutraceutical and cosmetic outcomes: preliminary studies. | chestnuts are a common food product in mediterranean countries, being recognized also for their beneficial effects on human health. nevertheless, during processing, these fruits generate a large amount of food by-products, such as shells and burs. in the present work, the macronutrient composition, vitamin e profile and amino acid content of the burs were determined in samples from three different portuguese regions (minho, trás-os-montes and beira-alta). the nutritional composition was similar ... | 2017 | 27990543 |
| promising new applications of castanea sativa shell: nutritional composition, antioxidant activity, amino acids and vitamin e profile. | the present study was aimed to assess the macronutrient composition and the amino acid and vitamin e profiles of castanea sativa shell from different production regions of portugal (minho, trás-os-montes and beira-alta). the nutritional composition was similar for all samples, with a high moisture content and low fat amounts. arginine and leucine were the predominant essential amino acids (eaa) accounting for 3.55-7.21% and 1.59-2.08%, respectively, for samples of the different production zones. ... | 2015 | 26190821 |
| off-label drug prescribing in a portuguese paediatric emergency unit. | many drugs are prescribed outside the terms of the marketing authorization ("off-label"). several studies have shown that this is a common practice in various european healthcare settings. | 2013 | 23054136 |
| implications of alteration processes on radon emanation, radon production rate and w-sn exploration in the panasqueira ore district. | alteration processes have strong impacts on the chemical and physical properties of rock masses. because they can affect the contents and the distribution of u as well as enhance the permeability of the bedrock, they may lead to a significant increase of radon release to the environment. however, their influence on radon emanation and radon production rate has yet to be properly assessed. to investigate the impact of alteration processes on the radiological properties, samples were collected in ... | 2017 | 29223909 |
| the intake of fish and the mercury concentration of fishing families at the city of imperatriz (ma), brazil. | significant levels of mercury exposure associated with fish intake have been demonstrated in riverine populations living in areas of mineral exploration as the basin of tapajós and madeira. in the tocantins region, although few studies, there is no evidence of human exposure through food. | 2016 | 27167645 |
| [chronic medication in the perioperative period: usage profile and risk management]. | currently, an increasing number of surgeries are performed in an older and higher risk population, due to the inherent comorbidity and polypharmacy associated with this population group. the characterization of drug usage profiles in the perioperative period is critically needed to understand the nature of adverse events and to achieve a more efficient iatrogenic risk management. | 2012 | 22713182 |
| physicochemical fingerprinting of thermal waters of beira interior region of portugal. | mineral natural waters and spas have been used for therapeutic purposes for centuries, with portugal being a very rich country in thermal waters and spas that are mainly distributed by northern and central regions where beira interior region is located. the use of thermal waters for therapeutic purposes has always been aroused a continuous interest, being dependent on physicochemical fingerprinting of this type of waters the indication for a treatment in a specific pathological condition. in the ... | 2017 | 27142760 |
| risk factors associated with hiv among men who have sex only with men and men who have sex with both men and women in three urban areas in mozambique. | using respondent-driven sampling (rds), an integrated biological behavioral survey among men that have sex with men (msm) enrolled 457 participants in maputo [63.0 % were msm who had sex with women (msmw)], 538 in beira (36.2 % msmw) and 330 in nampula-nacala (54.8 % msmw) in 2011. analysis suggests that msm who have sex only with men (msmo) had increased odds of having hiv (aor 2.7) compared to msmw. hiv among msmo associated with age, self-reported sti (aor 4.2), having a single male anal part ... | 2016 | 27059491 |
| general population and medical student perceptions of good and bad doctors in mozambique. | a key element of the doctor-patient relationship is to understand the patient's and doctor's perceptions of quality care. | 2011 | 21710412 |
| costs of illness due to endemic cholera. | economic analyses of cholera immunization programmes require estimates of the costs of cholera. the diseases of the most impoverished programme measured the public, provider, and patient costs of culture-confirmed cholera in four study sites with endemic cholera using a combination of hospital- and community-based studies. families with culture-proven cases were surveyed at home 7 and 14 days after confirmation of illness. public costs were measured at local health facilities using a micro-costi ... | 2012 | 21554781 |
| outpatient mental health services in mozambique: use and treatments. | to describe current outpatient mental health service use and treatments in mozambique, the authors reviewed registry entries for 2,071 outpatient psychiatric visits at the beira central hospital in sofala province from january 2012 to september 2014. service use was most common for schizophrenia, followed by epilepsy, delirium, and organic behavioral disorders. only 3% of consultations for schizophrenia were first-visit patients. treatment seeking among women was more likely for mood and neuroti ... | 2016 | 26828400 |
| effect of a neonatal resuscitation course on healthcare providers' performances assessed by video recording in a low-resource setting. | we assessed the effect of an adapted neonatal resuscitation program (nrp) course on healthcare providers' performances in a low-resource setting through the use of video recording. | 2015 | 26659661 |
| analysis of constructed wetland performance for irrigation reuse. | most of the wastewater treatment systems in small rural communities of the cova da beira region (portugal) consist of constructed wetlands (cw) with horizontal subsurface flow (hssf). it is believed that those systems allow the compliance of discharge standards as well as the production of final effluents with suitability for reuse. results obtained in a nine-month campaign in an hssf bed pointed out that cod and tss removal were lower than expected. a discrete sampling also showed that removal ... | 2010 | 20371927 |
| cost-effectiveness of new-generation oral cholera vaccines: a multisite analysis. | we evaluated the cost-effectiveness of a low-cost cholera vaccine licensed and used in vietnam, using recently collected data from four developing countries where cholera is endemic. our analysis incorporated new findings on vaccine herd protective effects. | 2009 | 19824189 |
| asthma is more frequently associated with non-allergic than allergic rhinitis in portuguese patients. | rhinitis prevalence is increasing worldwide and is frequently associated with asthma, for which it is a risk factor. the aims of the study were to characterise the adult population with rhinitis attending the cova da beira hospital allergy clinic, and to assess the relationship between rhinitis and asthma. | 2009 | 19593980 |
| integrated approach to the understanding of the degradation of an urban river: local perceptions, environmental parameters and geoprocessing. | the use of interdisciplinary approaches such as the proposed report provides a broad understanding of the relationship between people and the environment, revealing reliable aspects not previously considered in the study of this relationship. this study compiled evidence on the environmental degradation of an urbanized river over the past few decades, providing a diagnosis of the consequences of this process for the river, its ichthyofauna, and the local human population. | 2015 | 26370116 |
| correlates of hiv testing among men who have sex with men in three urban areas of mozambique: missed opportunities for prevention. | this is the first study to identify levels of recent hiv testing and associated factors among men who have sex with men (msm) in mozambique. using data from maputo (n = 493), beira (n = 572), and nampula/nacala (n = 347), collected via respondent-driven sampling in 2011, and excluding those with prior known infection, we found that 30.4 % [95 % confidence interval (ci) 25.0-36.3 %], 42.1 % (95 % ci 36.8-47.3 %) and 29.8 % (95 % ci 22.9-36.9 %), respectively, had recently tested for hiv (≤12 mont ... | 2015 | 25987189 |
| demographic, laboratory and clinical characterisation of adult portuguese asthmatic patients. | asthma is a heterogeneous chronic inflammatory condition characterised by reversible airway obstruction and hyperresponsiveness associated with underlying bronchial inflammation and structural changes. it represents an increasing health problem and is a huge burden on the patients, their families and society. the aim of the study was to characterise the adult asthmatic population attending a hospital allergy clinic between the years of 2003 and 2006. | 2007 | 17923071 |
| broadband molecular sensing with a tapered spoof plasmon waveguide. | unambiguous identification of low concentration chemical mixtures can be performed by broadband enhanced infrared absorption (beira). here we propose and numerically study a corrugated parallel plate waveguide (cppw) with gradient grooves which is capable of directly converting transmission modes to surface plasmon modes and could hence serve as a powerful chemical sensor. such a waveguide can be designed to exhibit a wide pass band covering an extended portion of a molecule absorption spectrum. ... | 2015 | 25968696 |
| socio-demographic, behavioral and health characteristics of underage female sex workers in mozambique: the need to protect a generation from hiv risk. | characteristics, hiv risk, and program coverage for underage female sex workers (fsw) are rarely systematically described worldwide. we compared characteristics of underage (15-17 years old) and adult (≥18 years old) fsw in three main urban areas of mozambique (maputo, beira and nampula) using data from three respondent-driven sampling surveys implemented in 2011-2012. among survey participants, 9.8 % (39/400) in maputo, 17.0 % (70/411) in beira and 25.6 % (110/429) in nampula were underage. ove ... | 2015 | 25931241 |
| willingness to participate in future hiv prevention trials in beira, mozambique. | in preparation for trials of new hiv prevention methods, willingness to participate (wtp) was assessed in beira, mozambique. a total of 1 019 women participating in an hiv incidence study, and 97 men participating in a separate wtp survey, were interviewed. when comparing the answers to questions that were identical in the two studies, wtp was higher among women than men for all prevention methods. among women, wtp was highest for trials evaluating daily oral pre-exposure prophylaxis (prep; 84.4 ... | 2014 | 25555105 |
| men who have sex with men in mozambique: identifying a hidden population at high-risk for hiv. | the population of men who have sex with men (msm) has been largely ignored in hiv-related policies and programming in mozambique and there is little information about the contribution of msm to the hiv epidemic. an integrated biological and behavioral study among msm using respondent-driven sampling was conducted in 2011 in maputo, beira and nampula/nacala. men who reported engaging in oral or anal sex with other men in the last 12 months answered a questionnaire and provided a blood sample for ... | 2015 | 25234252 |
| [a therapeutic approach in burkitt's lymphoma. 2 case reports from the hospital central da beira/mozambique]. | burkitt's lymphoma is the most common malignant tumor encountered in children (age peak 3 to 8 years) living in areas with endemic malaria tropica. in the hospital central da beira/mozambique, two children with burkitt's lymphoma were treated with cyclophosphamide. during the period covered by this report--august 1 to september 30, 2000--two of the required four treatment cycles were carried out, and both children experienced a remission. | 2001 | 11935660 |
| spectrum of pediatric cancers in mozambique: an analysis of hospital and population-based data. | the existing data provide little detail about the epidemiology of pediatric cancers in mozambique. we aimed at characterizing the spectrum of pediatric cancers (0-14 years) diagnosed in mozambique in two different calendar periods. data were obtained from the pathology department of the maputo central hospital (dp-hcm) (1999-2000 and 2009-2010), which receives virtually all samples for histopathological diagnosis in maputo, with the exception of leukemia, and from the population-based cancer reg ... | 2014 | 24852201 |
| multimorbidity in primary care in portugal (mm-pt): a cross-sectional three-phase observational study protocol. | multimorbidity is defined as the co-occurrence of more than one chronic disease in one person without assigning an index disease. this rapidly increasing phenomenon markedly influences patients' overall health, has major implications for effective provision of healthcare services and has a significant economic toll on individuals and society. since portugal is a country with a growing ageing population, a better understanding of the role of multimorbidity should be assessed. the aim of this stud ... | 2014 | 24531449 |
| nursing in another world. an african diary. | matorga mission is in the beira corridor and is guarded by zimbabwean soldiers as there are dangers of renamo guerilla raids. the mission cares for over a hundred children many of whom are war orphans. this is diana's first letter to the journal. i hope she will be sending us further letters at intervals. | 1991 | 1802100 |
| field evaluation of measles vaccine efficacy in mozambique. | monitoring measles vaccine efficacy is an important form of quality control in immunization programs. retrospective cohort studies of vaccine efficacy were conducted in mozambique with the aim of adopting this method for regular use. the authors studied 1,215 and 790 children aged 12-35 months in the cities of nampula and beira, respectively. in nampula (1985), vaccine efficacy was estimated to be 40%, and in beira (1986), it was estimated to be 59%. to investigate the possibility of falsely low ... | 1990 | 2404409 |
| patient and health system delay among patients with pulmonary tuberculosis in beira city, mozambique. | tb control is based on the rapid identification of cases and their effective treatment. however, many studies have shown that there are important delays in diagnosis and treatment of patients with tb. the purpose of this study was to assess the prevalence of and identify risk factors associated with patient delay and health system delay among newly diagnosed patients with pulmonary tb. | 2013 | 24499197 |
| oxidative metabolism of rye (secale cereale l.) after short term exposure to aluminum: uncovering the glutathione-ascorbate redox network. | one of the major limitations to plant growth and yield in acidic soils is the prevalence of soluble aluminum ions (al(3+)) in the soil solution, which can irreversible damage the root apex cells. nonetheless, many al-tolerant species overcome al toxicity and are well-adapted to acidic soils, being able to complete their life cycle under such stressful conditions. at this point, the complex physiological and biochemical processes inherent to al tolerance remain unclear, especially in what concern ... | 2016 | 27252711 |
| accumulation of uranium by aquatic plants in field conditions: prospects for phytoremediation. | a study was undertaken to determine uranium concentrations in water and aquatic plants in the uraniferous region of beiras, central portugal. samples were collected from running water (n=200) at places where aquatic species were observed. plant samples were collected from 28 species of submerged, free-floating and rooted emergent plants including 2 bryophytes and 1 pteridophyte. uranium concentrations in surface waters ranged from 0.23 to 1,217 μg l(-1). the aquatic plant species studied, includ ... | 2014 | 24239820 |
| allergic asthma and omalizumab--the experience at the centro hospitalar da cova da beira. | | 2015 | 23731772 |
| revalidation of pyxicephalus angusticeps parry, 1982 (anura: natatanura: pyxicephalidae), a bullfrog endemic to the lowlands of eastern africa. | pyxicephalus currently contains three recognized species, viz. p. adspersus, p. edulis and p. obbianus, the former two of which have a long history of confusion. parry (1982) described p. adspersus angusticeps from beira, mozambique, which was synonymized with p. edulis. we re-examine the taxonomic status of pyxicephalus taxa from mozambique, examining the types and contrasting them to congeners throughout africa. morphological characters previously used to delimit species in pyxicephalus are ex ... | 2013 | 24613871 |
| population size estimate of men who have sex with men, female sex workers, and people who inject drugs in mozambique: a multiple methods approach. | accurate estimates of key population size are necessary to design programs and policies to prevent and reduce new hiv infections and to monitor the dynamics of the epidemic. the first bio-behavioral surveillance surveys, with population size estimation activities, were conducted in mozambique in 2010 to 2014. | 2020 | 32815901 |
| kaolin, ascophyllum nodosum and salicylic acid mitigate effects of summer stress improving hazelnut quality. | various strategies are needed to mitigate the negative impact on or to increase fruit quality. the effect of spraying kaolin (k), ascophyllum nodosum (an) and salicylic acid (sa), in trees with and without irrigation, on quality and sensorial attributes of hazelnut (grada de viseu cultivar) was investigated during two consecutive years (2016 and 2017) in a commercial orchard located in moimenta da beira, portugal. | 2020 | 32648605 |
| population size estimate of men who have sex with men, female sex workers and people who inject drugs in mozambique-a multiple methods approach. | accurate estimates of key population size are necessary to design programs and policies to prevent and reduce new hiv infections and to monitor the dynamics of the epidemic. the first bio-behavioral surveillance (bbs) surveys, with population size estimation activities, were conducted in mozambique in 2010-2014. | 2020 | 32530856 |
| determinants of prevalent hiv infection and late hiv diagnosis among young women with two or more sexual partners in beira, mozambique. | the prevalence and determinants of hiv and late diagnosis of hiv in young women in beira, mozambique, were estimated in preparation for hiv prevention trials. | 2013 | 23691046 |
| suicide attempts and deaths in sofala, mozambique, from 2011 to 2014. | mozambique was recently estimated to have the highest suicide rate in africa. | 2016 | 27245814 |
| y-chromosome diversity in central portugal reveals signatures of ancient maritime expansions. | the genetic diversity of human populations in portugal results from several different demographic events that occurred in distinct prehistorical and historical periods. the main objective of this study was to examine if patterns of y-chromosome diversity explained by ancient maritime mediterranean expansions can be observed in coimbra district (central-west region of portugal). a total of 125 male dna samples were typed for 16 y-snps and eight y-strs using standard molecular methodologies. thirt ... | 2013 | 24620564 |
| absorption ångström exponents of aerosols and light absorbing carbon (lac) obtained from in situ data in covilhã, central portugal. | a field campaign was conducted from october 2009 to july 2010 at covilhã, a small town located in the region of beira interior (portugal) in the interior of the iberian peninsula. the ambient light-absorption coefficient, σ(a) (522 nm), obtained from a particle soot absorption photometer (psap), presented a daily mean value of 12.1 mm⁻¹ (std = 7.3 mm⁻¹). the wavelength dependence of aerosol light absorption is investigated through the ångström parameter, α(a). the α(a) values for the pair of wav ... | 2012 | 23138695 |
| hiv-exposed infant follow-up in mozambique: formative research findings for the design of a cluster randomized controlled trial to improve testing and art initiation. | early infant diagnosis (eid) of hiv-exposed and initiation of hiv-positive infants on anti-retroviral therapy (art) requires a well-coordinated cascade of care. loss-to-follow-up (ltfu) can occur at multiple steps and effective eid is impeded by human resource constraints, difficulty with patient tracking, and long waiting periods. the objective of this research was to conduct formative research to guide the development of an intervention to improve the pediatric hiv care cascade in central moza ... | 2020 | 32183779 |
| biogeochemistry of uranium in the soil-plant and water-plant systems in an old uranium mine. | the present study highlights the uranium (u) concentrations in water-soil-plant matrices and the efficiency considering a heterogeneous assemblage of terrestrial and aquatic native plant species to act as the biomonitor and phytoremediator for environmental u-contamination in the sevilha mine (uraniferous region of beiras, central portugal). a total of 53 plant species belonging to 22 families was collected from 24 study sites along with ambient soil and/or water samples. the concentration of u ... | 0 | 27314898 |
| noisy ocular recognition based on three convolutional neural networks. | in recent years, the iris recognition system has been gaining increasing acceptance for applications such as access control and smartphone security. when the images of the iris are obtained under unconstrained conditions, an issue of undermined quality is caused by optical and motion blur, off-angle view (the user's eyes looking somewhere else, not into the front of the camera), specular reflection (sr) and other factors. such noisy iris images increase intra-individual variations and, as a resu ... | 2017 | 29258217 |
| national tb program shortages as potential factor for poor-quality tb care cascade: healthcare workers' perspective from beira, mozambique. | mozambique is one of the countries with the deadly implementation gaps in the tuberculosis (tb) care and services delivery. in-hospital delays in tb diagnosis and treatment, transmission and mortality still persist, in part, due to poor-quality of tb care cascade. | 2020 | 32059032 |