Publications

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malaria transmission in dakar: a two-year survey.according to entomological studies conducted over the past 30 years, there was low malaria transmission in suburb of dakar but little evidence of it in the downtown area. however; there was some evidence of local transmission based on reports of malaria among permanent residents. an entomological evaluation of malaria transmission was conducted from may 2005 to october 2006 in two areas of dakar.200818796138
highly focused anopheline breeding sites and malaria transmission in dakar.urbanization has a great impact on the composition of the vector system and malaria transmission dynamics. in dakar, some malaria cases are autochthonous but parasite rates and incidences of clinical malaria attacks have been recorded at low levels. ecological heterogeneity of malaria transmission was investigated in dakar, in order to characterize the anopheles breeding sites in the city and to study the dynamics of larval density and adult aggressiveness in ten characteristically different urb ...200919552809
yellow fever virus exhibits slower evolutionary dynamics than dengue virus.although yellow fever has historically been one of the most important viral infections of humans, relatively little is known about the evolutionary processes that shape its genetic diversity. similarly, there is limited information on the molecular epidemiology of yellow fever virus (yfv) in africa even though it most likely first emerged on this continent. through an analysis of complete e gene sequences, including a newly acquired viral collection from central and west africa (senegal, cameroo ...201019889759
Conditions of malaria transmission in Dakar from 2007 to 2010.Previous studies in Dakar have highlighted the spatial and temporal heterogeneity of Anopheles gambiae s.l. biting rates. In order to improve the knowledge of the determinants of malaria transmission in this city, the present study reports the results of an extensive entomological survey that was conducted in 45 areas in Dakar from 2007 to 2010.201122018223
scoping review of the zika virus literature.the global primary literature on zika virus (zikv) (n = 233 studies and reports, up to march 1, 2016) has been compiled using a scoping review methodology to systematically identify and characterise the literature underpinning this broad topic using methods that are documented, updateable and reproducible. our results indicate that more than half the primary literature on zikv has been published since 2011. the articles mainly covered three topic categories: epidemiology of zikv (surveillance an ...201627244249
zika virus: the latest newcomer.since the beginning of this century, humanity has been facing a new emerging, or re-emerging, virus threat almost every year: west nile, influenza a, avian flu, dengue, chikungunya, sars, mers, ebola, and now zika, the latest newcomer. zika virus (zikv), a flavivirus transmitted by aedes mosquitoes, was identified in 1947 in a sentinel monkey in uganda, and later on in humans in nigeria. the virus was mainly confined to the african continent until it was detected in south-east asia the 1980's, t ...201627148186
zika virus emergence in mosquitoes in southeastern senegal, 2011.zika virus (zikv; genus flavivirus, family flaviviridae) is maintained in a zoonotic cycle between arboreal aedes spp. mosquitoes and nonhuman primates in african and asian forests. spillover into humans has been documented in both regions and the virus is currently responsible for a large outbreak in french polynesia. zikv amplifications are frequent in southeastern senegal but little is known about their seasonal and spatial dynamics. the aim of this paper is to describe the spatio-temporal pa ...201425310102
larval ecology of mosquitoes in sylvatic arbovirus foci in southeastern senegal.although adult mosquito vectors of sylvatic arbovirus [yellow fever (yfv), dengue-2 (denv-2) and chikungunya (chikv)] have been studied for the past 40 years in southeastern senegal, data are still lacking on the ecology of larval mosquitoes in this area. in this study, we investigated the larval habitats of mosquitoes and characterized their seasonal and spatial dynamics in arbovirus foci.201223216815
oviposition ecology and species composition of aedes spp. and aedes aegypti dynamics in variously urbanized settings in arbovirus foci in southeastern côte d'ivoire.aedes mosquito-transmitted outbreaks of dengue and yellow fever have been reported from rural and urban parts of côte d'ivoire. the present study aimed at assessing aedes spp. oviposition ecology in variously urbanized settings within arbovirus foci in southeastern côte d'ivoire.201627682270
impact of mosquito bites on asexual parasite density and gametocyte prevalence in asymptomatic chronic plasmodium falciparum infections and correlation with ige and igg titers.an immunomodulatory role of arthropod saliva has been well documented, but evidence for an effect on plasmodium sp. infectiousness remains controversial. mosquito saliva may orient the immune response toward a th2 profile, thereby priming a th2 response against subsequent antigens, including plasmodium. orientation toward a th1 versus a th2 profile promotes igg and ige proliferation, respectively, where the former is crucial for the development of an efficient antiparasite immune response. here ...201222451520
identification of wolbachia strains in mosquito disease vectors.wolbachia bacteria are common endosymbionts of insects, and some strains are known to protect their hosts against rna viruses and other parasites. this has led to the suggestion that releasing wolbachia-infected mosquitoes could prevent the transmission of arboviruses and other human parasites. we have identified wolbachia in kenyan populations of the yellow fever vector aedes bromeliae and its relative aedes metallicus, and in mansonia uniformis and mansonia africana, which are vectors of lymph ...201223185484
field evaluation of natural human odours and the biogent-synthetic lure in trapping aedes aegypti, vector of dengue and chikungunya viruses in kenya.methods currently used in sampling adult aedes aegypti, the main vector of dengue and chikungunya viruses are limited for effective surveillance of the vector and accurate determination of the extent of virus transmission during outbreaks and inter - epidemic periods. here, we document the use of natural human skin odours in baited traps to improve sampling of adult ae. aegypti in two different endemic areas of chikungunya and dengue in kenya - kilifi and busia counties. the chemistry of the vol ...201425246030
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