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antiangiogenic metabolites from a marine-derived fungus, hypocrea vinosa.the aims of this study were to investigate the role of tyrosine kinase in intracellular signaling and to search for lead compounds with tyrosine kinase inhibitory activity from metabolites of marine-derived fungi. we initially prepared 400 extracts from 200 species of marine fungi and then subjected them to a tyrosine kinase screening assay using human umbilical vein endothelial cell lysate. tyrosine kinase inhibitory activity was observed among certain metabolites of hypocrea vinosa. we isolate ...201020192239
hypocrea rufa/trichoderma viride: a reassessment, and description of five closely related species with and without warted conidia.the type species of the genus hypocrea (hypocreaceae, hypocreales, ascomycota, fungi), h. rufa, is re-defined and epitypified using a combination of phenotype (morphology of teleomorphs and anamorphs, and characteristics in culture) and phylogenetic analyses of the translation-elongation factor 1alpha gene. its anamorph, t. viride, the type species of trichoderma, is re-described and epitypified. eidamia viridescens is combined as trichoderma viridescens and is recognised as one of the most morp ...200618490991
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