| in vitro combinations of natamycin with voriconazole, itraconazole and micafungin against clinical fusarium strains causing keratitis. | fusarium species cause a broad spectrum of infections, from superficial to disseminated disease. because fusarium species are intrinsically resistant to most antifungal drugs, new approaches are needed. the aim of the present study was to evaluate the in vitro combination of natamycin with currently used antifungal drugs. | 2016 | 26702918 |
| comparison of dna microarray, loop-mediated isothermal amplification (lamp) and real-time pcr with dna sequencing for identification of fusarium spp. obtained from patients with hematologic malignancies. | the performance of three molecular biology techniques, i.e., dna microarray, loop-mediated isothermal amplification (lamp), and real-time pcr were compared with dna sequencing for properly identification of 20 isolates of fusarium spp. obtained from blood stream as etiologic agent of invasive infections in patients with hematologic malignancies. dna microarray, lamp and real-time pcr identified 16 (80%) out of 20 samples as fusarium solani species complex (fssc) and four (20%) as fusarium spp. t ... | 2017 | 28324245 |
| fatal disseminated infection with fusarium petroliphilum. | members of the fusarium solani species complex (fssc) are causing the majority of the fusariosis in humans. disseminated fusariosis has a high mortality and is predominantly observed in patients with leukemia. here, we present the case of a fatal infection by a fusarium strain with a degenerated phenotype, in a patient with acute lymphatic leukemia. multiple nasal and skin biopsies as well as blood cultures yielded fungal growth, while in direct and histopathological examination of biopsy materi ... | 2015 | 25234793 |
| phylogenetic relationships among members of the fusarium solani species complex in human infections and the descriptions of f. keratoplasticum sp. nov. and f. petroliphilum stat. nov. | fusarium species are frequently associated with mycotic keratitis and, to a lesser extent, cases of localized and disseminated infections. the fusarium solani species complex (fssc) is the most common group of fusaria associated with human infectious diseases. several studies to date have revealed dozens of strongly supported phylogenetic species within this important evolutionary clade, though little work has been done to improve the taxonomy and understanding of the reproductive mode and pheno ... | 2013 | 23396261 |
| biofilm formation and resistance to fungicides in clinically relevant members of the fungal genus fusarium. | clinically relevant members of the fungal genus, fusarium, exhibit an extraordinary genetic diversity and cause a wide spectrum of infections in both healthy individuals and immunocompromised patients. generally, fusarium species are intrinsically resistant to all systemic antifungals. we investigated whether the presence or absence of the ability to produce biofilms across and within fusarium species complexes is linked to higher resistance against antifungals. a collection of 41 fusarium strai ... | 2018 | 29371509 |
| in vitro resistance of clinical fusarium species to amphotericin b and voriconazole using the eucast antifungal susceptibility method. | susceptibility testing using the eucast-afst method against 39 clinical fusarium strains consecutively collected from local and invasive infections during the last 10years assessed the in vitro activities of amphotericin b (amb) and triazole antifungal agents. in addition, the susceptibility pattern of 12 reference strains from the cbs-knaw fungal biodiversity centre (cbs) was evaluated. in particular fusarium petroliphilum and f. solani sensu lato were involved in disseminated infections and kn ... | 2016 | 27312690 |