| the association between exposure to aflatoxin, mutation in tp53, infection with hepatitis b virus, and occurrence of liver disease in a selected population in hyderabad, india. | aflatoxin b1 is a carcinogen produced by aspergillus flavus and a few related fungi that are often present in many food substances. it interacts synergistically with hepatitis b or c virus (hbv, hbc) infection, thereby increasing the risk of hepatocellular carcinoma (hcc). the g to t transversion at the third position of codon 249 (agg) of the tp53 gene, substituting arginine to serine, is the most common aflatoxin-induced mutation linked to hcc. this study examined mutations in tp53 by pcr-rflp ... | 2014 | 24657665 |