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[genomic characteristics of coxsakievirus a16 isolated in henan province].to reveal the genomic sequence characteristics of coxsackievirus a16 (coxa16) strain isolated from patients with hand-foot-mouth disease (hfmd) in henan province. a total of 406 samples were detected by reverse-transcription polymerase chain reaction (rt-pcr) and cell-culture-based isolation of coxsackievirus a16. the whole genome of coxa16 isolate was amplified using 10 pairs of primers, the sequences were analyzed and phylogenetic tree was generated by bioinformatics software. the full length ...201222519172
epidemiology and etiology of hand, foot, and mouth disease in fujian province, 2008-2014.millions of cases of hand, foot, and mouth disease (hfmd) have been reported annually in mainland china since 2008. in this study, we investigated the epidemiology and etiology of an hfmd epidemic in fujian province, which is located in subtropical southeastern china. our study found similar epidemiological features of hfmd in southern areas of china, including seasonality and demographic distribution, as well as correlation between severity of illness and serotype. at least 22 serotypes of othe ...201727796546
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