| complete sequence determination of a novel reptile iridovirus isolated from soft-shelled turtle and evolutionary analysis of iridoviridae. | soft-shelled turtle iridovirus (stiv) is the causative agent of severe systemic diseases in cultured soft-shelled turtles (trionyx sinensis). to our knowledge, the only molecular information available on stiv mainly concerns the highly conserved stiv major capsid protein. the complete sequence of the stiv genome is not yet available. therefore, determining the genome sequence of stiv and providing a detailed bioinformatic analysis of its genome content and evolution status will facilitate furthe ... | 2009 | 19439104 |
| involvement of the mitogen-activated protein kinase pathway in soft-shelled turtle iridovirus-induced apoptosis. | iridoviruses are large dna viruses that infect invertebrates and poikilothermic vertebrates, and result in significant economic losses in aquaculture production, and drastic declines in amphibian populations. soft-shelled turtle iridovirus (stiv) is the causative agent of severe systemic diseases in farm-raised soft-shelled turtles (trionyx sinensis). in the present study, the mechanisms of stiv-induced cell death and the roles of the mitogen-activated protein kinase (mapk) signaling pathway wer ... | 2011 | 21442306 |
| characterization of dna aptamers generated against the soft-shelled turtle iridovirus with antiviral effects. | soft-shelled turtle iridovirus (stiv) causes severe systemic disease in farmed soft-shelled turtles (trionyx sinensis). more efficient methods of controlling and detecting stiv infections are urgently needed. | 2015 | 26419355 |
| ifn-γ in turtle: conservation in sequence and signalling and role in inhibiting iridovirus replication in chinese soft-shelled turtle pelodiscus sinensis. | the ifn-γ gene was identified in a turtle, the chinese soft-shelled turtle, pelodiscus sinensis, with its genome consisting of 4 exons and 3 introns. the deduced amino acid sequence of this gene contains a signal peptide, an ifn-γ family signature motif (130)iqrkavnelfpt, an nls motif (155)krkr and three potential n-glycosylation sites. as revealed by real-time quantitative pcr, the gene was constitutively expressed in all tested organs/tissues, with higher level observed in blood, intestine and ... | 2014 | 24239708 |
| a new iridovirus isolated from soft-shelled turtle. | a virus was isolated from soft-shelled turtle (trionyx sinensis) with 'red neck disease' on a farm in shenzhen, china, the virus multiplied and caused a cytopathogenic effect (cpe) at 15-30 degrees c in co, fhm, ck and bf-2 cells. the optimum conditions for replication was in co cells at 25-30 degrees c. the virus was sensitive to chloroform treatment, acid (ph 3) or alkaline (ph 10) conditions and heating at 56 degrees c for 30 min. treatment with 5-iodo-2-deoxyuridine (iudr) inhibited viral re ... | 1999 | 10509727 |