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overview of studies on liver carcinogenesis in english sole from puget sound; evidence for a xenobiotic chemical etiology. ii: biochemical studies.the levels of aromatic hydrocarbons in sediments of puget sound, washington, are positively correlated with the prevalence of hepatic neoplasms and related lesions in english sole (parophrys vetulus). to investigate the biochemical processes involved in chemical carcinogenesis in fish from puget sound, we have studied the uptake, activation, and detoxication of polycyclic aromatic hydrocarbons (pahs) in english sole, and have compared these data to pah metabolism in a related species, starry flo ...19902360039
pathology of hepatomas and other liver abnormalities in english sole (parophrys vetulus) from the duwamish river estuary, seattle, washington.liver abnormalities were found, by gross and histopathologic examination, in 92% of the english sole (parophrys vetulus) from the duwamish river estuary, seattle, washington. hepatomas were found in 32% (20 of 62) of the english sole. other observed liver aberrations included increased fatty vacuolation, congestion, structure disarray, increased size and number of melanin-macrophage centers, centrolobular fatty degeneration and necrosis, increased amounts of perivascular connective tissue, inter ...1993206710
time trends of persistent organic pollutants in benthic and pelagic indicator fishes from puget sound, washington, usa.we modeled temporal trends in polychlorinated biphenyls (pcbs), polybrominated diphenyl ethers (pbdes), and dichlorodiphenyltrichloroethane and its metabolites (ddts) in two indicator fish species representing benthic and pelagic habitats in puget sound, washington, usa. english sole (parophrys vetulus, benthic) index sites and larger-scale pacific herring (clupea pallasii, pelagic) foraging areas represented a wide range of possible contamination conditions, with sampling locations situated adj ...201728528416
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