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molecular evolution of the haemagglutinin-neuraminidase gene in human parainfluenza virus type 3 isolates from children with acute respiratory illness in yamagata prefecture, japan.we conducted detailed genetic analyses of the haemagglutinin-neuraminidase (hn) gene in 272 human parainfluenza virus type 3 (hpiv3) isolates from children with acute respiratory illness during the period 2002-2009 in yamagata prefecture, japan. a phylogenetic tree reconstructed by the bayesian markov chain monte carlo method showed that the strains diversified at around 1946 and that the rate of molecular evolution was 1.10×10(-3) substitutions per site per year. identity was high among the pre ...201424464692
seasonal patterns of respiratory syncytial virus, influenza a virus, human metapneumovirus, and parainfluenza virus type 3 infections on the basis of virus isolation data between 2004 and 2011 in yamagata, japan.most acute respiratory infections (aris) are thought to be associated with respiratory viruses that cause similar symptoms. therefore, assessment of clinical and epidemiologic features of these viruses is important for diagnosing a viral infection. we collected 13,325 nasopharyngeal specimens from patients with aris and isolated the virus using a microplate method involving 7 cell lines between 2004 and 2011 in yamagata, japan. we isolated a total of 5,483 viruses. respiratory syncytial virus (r ...201323514911
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