| [isolation and sequencing of vp1 region of enterovirus 71 strains in zhejiang, china]. | to study the gene characterization of enterovirus 71 (ev71) virus strains isolated from clinical specimens of children with hand-foot-and-mouth disease (hfmd) in zhejiang province. | 2005 | 16676593 |
| detection of human enterovirus 71 and coxsackievirus a16 in children with hand, foot and mouth disease in china. | the aims of the present study were to investigate the genetic characteristics of enterovirus 71 (ev71) and coxsackievirus a16 (cva16) strains in china and to evaluate the relationship between the genotypes of cva16 and ev71 and their geographical distribution. a total of 399 stool specimens were collected from children with symptoms of hand, foot and mouth disease (hfmd) in zhejiang province. the presence of enteroviruses was determined ... | 2012 | 22218731 |
| epidemiological characteristics and spatial-temporal clusters of hand, foot, and mouth disease in zhejiang province, china, 2008-2012. | hand, foot and mouth disease (hfmd) is one of the major public health concerns in china. being the province with high incidence rates of hfmd, the epidemiological features and the spatial-temporal patterns of zhejiang province were still unknown. the objective of this study was to investigate the epidemiological characteristics and the high-incidence clusters, as well as explore some potential risk factors. the surveillance data of hfmd during 2008-2012 were collected from the communicable disea ... | 2015 | 26422015 |
| clinical and epidemiological characteristics of adult hand, foot, and mouth disease in northern zhejiang, china, may 2008-november 2013. | hand, foot, and mouth disease (hfmd) is an infectious disease typically caused by enterovirus 71 (ev71) and coxsackievirus a16. the incidence of hfmd appears to be increasing across the asia pacific region, with deaths occurring predominantly among children. therefore, most hfmd reports focus on children and few have studied hfmd in adults. however, more adult hfmd cases may be seen in the foreseeable future as a result of global warming, continued viral evolution, and an increase in traveling. ... | 2014 | 24885052 |
| enterovirus infection in children attending two outpatient clinics in zhejiang province, china. | enteroviruses are responsible for hand, foot, and mouth disease, and have caused many deaths in china during recent years. but the natural history of enterovirus infection in children, especially asymptomatic children, is not yet clear. from april 2011 to may 2012, 505 stool and throat swab samples of children attending outpatients clinics in two hospitals were collected weekly to test for enterovirus 71, coxsackievirus a16, and other enterovirus nucleic acids by real-time rt-pcr. two hundred si ... | 2014 | 24519430 |
| epidemiologic features of enterovirus 71-associated hand-foot-and-mouth disease from 2009 to 2013 in zhejiang, china. | enterovirus 71 (ev71) usually causes hand-foot-and-mouth disease (hfmd) with severe clinical symptoms and even deaths in china. there is no efficient antiviral drug to protect against severe ev71-associated hfmd, making the development of ev71 vaccines therefore a priority. however, the potential target subject population(s) to be immunized with ev71 vaccine are not well understood. in this study, we characterized the epidemiology regarding ev71-associated hfmd on the basis of provincial-level s ... | 2016 | 28042848 |
| [retrospective analysis of clinical and epidemiological characteristics of hand-foot-and-mouth disease deceased cases in zhejiang province]. | to understand the clinical and epidemiological characteristics of hand-foot-and-mouth disease (hfmd) deceased cases. | 2013 | 23927799 |
| [clinical stages and outcomes of severe cases on hand, foot and mouth disease]. | objective: to understand the characteristics and relation of clinical stage and outcome of severe cases on hand, foot and mouth disease (hfmd) and to establish the evaluation method for understanding severity of this disease. methods: according to factors as geographical location, economic and epidemic levels, five provinces (henan, shandong, yunnan, zhejiang and sichuan provinces) were selected. reported severe cases of hfmd from the national notifiable diseases reporting system were selected r ... | 2017 | 28651405 |