| molecular and serological analyses of two bovine rotaviruses (b-11 and b-60) causing calf scours in australia. | fecal specimens from 78 calves involved in outbreaks of calf diarrhea which occurred in three farms in victoria, australia, in 1988 were analyzed for rotaviruses. thirty-eight samples were positive for group a virus antigen by enzyme-linked immunosorbent assay, and 20 of these contained viral double-stranded rnas that could be detected by polyacrylamide gel electrophoresis. two major electropherotypes could be observed, and a representative isolate of each electropherotype (isolates b-11 and b-6 ... | 1992 | 1310336 |
| use of serotype-specific monoclonal antibodies to study the epidemiology of rotavirus infection. | the development of an enzyme immunoassay (eia) capable of serotyping human rotavirus (hrv) in faecal extracts has enabled us to retrospectively study the epidemiology of rotavirus infection in melbourne. of 552 stored specimens obtained from individuals with rotavirus-associated gastroenteritis between 1975 and 1986, the serotype could be determined in 62%. infection was most prevalent in two groups, neonates and children aged between 12 and 24 months. in these groups infection was due to differ ... | 1988 | 2828532 |
| sequence conservation within neutralization epitope regions of vp7 and vp4 proteins of human serotype g4 rotavirus isolates. | serotype g4 rotavirus isolates causing four separate epidemics of severe diarrhoea in young children in melbourne, australia (from 1974-1990) were investigated for sequence variation in genes encoding the outer capsid proteins, vp4 and vp7. complementary dna of the gene encoding the major outer capsid neutralization antigen, vp7, of eighteen isolates was synthesized and amplified by coupled reverse transcription and polymerase chain reaction. direct sequencing methods were used to derive the ded ... | 1993 | 7504915 |
| genetic and antigenic characterization of a serotype g6 human rotavirus isolated in melbourne, australia. | an unusual rotavirus strain, mg6, was isolated from a 16-month-old child admitted to hospital with acute gastroenteritis. the virus could not be serotyped (g-typed) by enzyme immunoassay using standard reagents specific for common serotypes of human group a rotaviruses. nucleotide sequencing of cdna derived from the gene encoding the outer capsid protein, vp7, and deduction of the vp7 amino acid sequence indicated that this strain belonged to serotype g6, a serotype normally associated with viru ... | 1995 | 8636702 |
| g3p2 rotaviruses causing diarrhoeal disease in neonates differ in vp4, vp7 and nsp4 sequence from g3p2 strains causing asymptomatic neonatal infection. | during longitudinal epidemiological studies of rotavirus infections in children in melbourne, australia human g3p2 rotavirus strains causing asymptomatic or symptomatic infections have been identified. eleven strains (as strains) associated with asymptomatic infection of newborn babies from 1974-1984, and five strains (s strains) associated with symptomatic infection of newborn babies (4) or a 22 week old infant (1) during 1980-1986 were studied. the entire nucleotide sequences of genes coding f ... | 1996 | 8893789 |
| genetic homogeneity of human serotype g1 rotaviruses isolated during a single epidemic season: implications for vaccine strategies. | the extent of genetic variation of rotavirus isolates representing the common serotype g1 circulating in australian urban centres during 1996 was investigated. the sequences of the major outer capsid glycoprotein, vp7, of three isolates from brisbane, sydney and melbourne were determined and found to be highly conserved (> 99% nucleotide identity, > 98.3% amino acid identity and > 99% amino acid similarity). in particular, the sequences of the neutralisation epitope regions were absolutely conse ... | 1999 | 10672345 |
| australia's notifiable diseases status, 2001: annual report of the national notifiable diseases surveillance system. | in 2001 there were 104,187 notifications of communicable diseases in australia reported to the national notifiable diseases surveillance system (nndss). the number of notifications in 2001 was an increase of 16 per cent of those reported in 2000 (89,740) and the largest annual total since the nndss commenced in 1991. in 2001, nine new diseases were added to the list of diseases reported to nndss and four diseases were removed. the new diseases were cryptosporidiosis, laboratory-confirmed influen ... | 2003 | 12725505 |
| annual report: surveillance of adverse events following immunisation in australia, 2008. | this report summarises australian passive surveillance data for adverse events following immunisation (aefi) reported to the therapeutic goods administration (tga) for 2008, and describes reporting trends over the 9-year period 2000 to 2008. there were 1,542 aefi records for vaccines administered in 2008. this was an annual aefi reporting rate of 7.2 per 100,000 population, a 5% decrease compared with 2007. the majority of aefi reports described non-serious events while 10% (n = 152) were classi ... | 2009 | 20301966 |