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maternal antibodies to rotavirus: could they interfere with live rotavirus vaccines in developing countries?past experience with live oral vaccines including licensed rotavirus vaccines demonstrates a trend towards reduced vaccine efficacy in developing countries compared with developed countries. the reasons behind this disparity are not well understood. transplacental transfer of maternal antibodies and breast milk ingestion may attenuate vaccine responses in infants in developing countries where rotavirus infections are endemic, and maternal antibody levels are high. we examined the prevalence and ...201021147127
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