Publications

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breastfeeding: breast milk banks and human immunodeficiency virus.hiv in infants and children in zimbabwe is virtually limited to vertical transmission. less than 5 cases of transfusion acquired hiv infections have been documented to date. zimbabwe was the third country in the world after the united states, to screen transfusion blood and blood products. the controversy of hiv transmission through breast milk is still far from resolved. in developing countries, breast-milk substitutes for formulae are not only prohibitively expensive but dangerous because of u ...19902092885
hospital-based study of sexually transmitted diseases at murewa rural district hospital, zimbabwe 1991-1992.in zimbabwe, sexually transmitted diseases are highly prevalent and represent a significant amount of the workload for physicians.19957709319
mortality in the first 2 years among infants born to human immunodeficiency virus-infected women in harare, zimbabwe.transmission of human immunodeficiency virus (hiv) and mortality was studied among infants of infected women in zimbabwe. of 367 infants born to hiv-infected women, 72 (19.6%) died compared with 20 (5.4%) of 372 infants of uninfected women (p < .01). infection by hiv dna polymerase chain reaction among infants who survived >7 days and died within 2 years could be assessed in 87% (58/67) of infants of infected women and 83% (5/6) of infants of uninfected women; transmission occurred in 40 of 58 i ...19989652429
relationship of human herpesvirus 8 peripheral blood virus load and kaposi's sarcoma clinical stage.to determine the relationship between human herpesvirus 8 (hhv-8 or kaposi's sarcoma-associated herpesvirus) peripheral blood virus load and kaposi's sarcoma (ks) clinical stage.200011061651
relationship of kaposi sarcoma (ks)-associated herpesvirus viremia and ks disease in zimbabwe.the relationship between kaposi sarcoma-associated herpesvirus (kshv) viremia and ks disease was investigated in 500 subjects who received treatment in harare, zimbabwe. subjects were grouped by results of human immunodeficiency virus (hiv) type 1 serological tests, ks diagnosis, and ks clinical stage. the plasma kshv dna concentration was associated with concomitant ks and hiv-1 infection (aids-ks; p<.001) and aids-ks clinical stage (p=.01). plasma kshv dna levels were greater in aids-ks than i ...200312715309
high rates of clustering of strains causing tuberculosis in harare, zimbabwe: a molecular epidemiological study.we examined the pattern of tuberculosis (tb) transmission (i.e., reactivation versus recent transmission) and the impact of human immunodeficiency virus (hiv) infection in harare, zimbabwe. consecutive adult smear-positive pulmonary tb patients presenting to an urban hospital in harare were enrolled. a detailed epidemiological questionnaire was completed, and tests for hiv type 1 and cd4 cell counts were performed for each patient. molecular fingerprinting of the genomic dna recovered from cultu ...200415472306
human immunodeficiency virus (hiv) types western blot (wb) band profiles as potential surrogate markers of hiv disease progression and predictors of vertical transmission in a cohort of infected but antiretroviral therapy naïve pregnant women in harare, zimbabwe.expensive cd4 count and viral load tests have failed the intended objective of enabling access to hiv therapy in poor resource settings. it is imperative to develop simple, affordable and non-subjective disease monitoring tools to complement clinical staging efforts of inexperienced health personnel currently manning most healthcare centres because of brain drain. besides accurately predicting hiv infection, sequential appearance of specific bands of wb test offers a window of opportunity to dev ...201121211021
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