| further studies on neonatal rotavirus infections. | forty newborn babies who were shown to be excreting rotaviruses within a few days of birth were tested daily for one month. most were found to excrete virus for only a short period of time. in 48% of babies, virus was found on one day only, in 25% it was present for two days, and in 10% for three days. most of these infections did not appear to confer lasting immunity. only 21% of young children who excreted virus as neonates had detectable circulating complement-fixing antibodies when eight to ... | 1980 | 6244482 |
| sequence conservation within neutralization epitope regions of vp7 and vp4 proteins of human serotype g4 rotavirus isolates. | serotype g4 rotavirus isolates causing four separate epidemics of severe diarrhoea in young children in melbourne, australia (from 1974-1990) were investigated for sequence variation in genes encoding the outer capsid proteins, vp4 and vp7. complementary dna of the gene encoding the major outer capsid neutralization antigen, vp7, of eighteen isolates was synthesized and amplified by coupled reverse transcription and polymerase chain reaction. direct sequencing methods were used to derive the ded ... | 1993 | 7504915 |
| genetic homogeneity of human serotype g1 rotaviruses isolated during a single epidemic season: implications for vaccine strategies. | the extent of genetic variation of rotavirus isolates representing the common serotype g1 circulating in australian urban centres during 1996 was investigated. the sequences of the major outer capsid glycoprotein, vp7, of three isolates from brisbane, sydney and melbourne were determined and found to be highly conserved (> 99% nucleotide identity, > 98.3% amino acid identity and > 99% amino acid similarity). in particular, the sequences of the neutralisation epitope regions were absolutely conse ... | 1999 | 10672345 |
| australia's notifiable diseases status, 2001: annual report of the national notifiable diseases surveillance system. | in 2001 there were 104,187 notifications of communicable diseases in australia reported to the national notifiable diseases surveillance system (nndss). the number of notifications in 2001 was an increase of 16 per cent of those reported in 2000 (89,740) and the largest annual total since the nndss commenced in 1991. in 2001, nine new diseases were added to the list of diseases reported to nndss and four diseases were removed. the new diseases were cryptosporidiosis, laboratory-confirmed influen ... | 2003 | 12725505 |
| annual report: surveillance of adverse events following immunisation in australia, 2008. | this report summarises australian passive surveillance data for adverse events following immunisation (aefi) reported to the therapeutic goods administration (tga) for 2008, and describes reporting trends over the 9-year period 2000 to 2008. there were 1,542 aefi records for vaccines administered in 2008. this was an annual aefi reporting rate of 7.2 per 100,000 population, a 5% decrease compared with 2007. the majority of aefi reports described non-serious events while 10% (n = 152) were classi ... | 2009 | 20301966 |
| case-control evaluation of the effectiveness of the g1p[8] human rotavirus vaccine during an outbreak of rotavirus g2p[4] infection in central australia. | the human rotavirus vaccine was evaluated during an outbreak of rotavirus g2p[4] infection in central australia. no overall protective effect against hospitalization was demonstrated, raising concerns over the durability of vaccine protection against heterotypic strains. | 2011 | 21288843 |