Publications

pandemic threat posed by avian influenza a viruses.	influenza pandemics, defined as global outbreaks of the disease due to viruses with new antigenic subtypes, have exacted high death tolls from human populations. the last two pandemics were caused by hybrid viruses, or reassortants, that harbored a combination of avian and human viral genes. avian influenza viruses are therefore key contributors to the emergence of human influenza pandemics. in 1997, an h5n1 influenza virus was directly transmitted from birds in live poultry markets in hong kong ...	2001	11148006
sequence analysis and receptor specificity of the hemagglutinin of a recent influenza h2n2 virus isolated from chicken in north america.	influenza viruses bind host cells following an interaction between the viral hemagglutinin (ha) protein and host cell sialylated glycoproteins and glycolipids. differences in binding affinities of the has for different types of sialic acid linkages (alpha2-3 vs. alpha2-6) contribute to determining the host range of an influenza virus. the ability of an avian influenza virus ha to bind the human form of the receptor may be one requirement for an avian virus to propagate in the human population. i ...	2006	16575526