| infection of newborn taiwan monkeys (macaca cyclopis) with human adenovirus type 12 and simian virus 40. | for testing biological response of newborn taiwan monkeys to infection of human adenovirus type 12 (ad12) and simian virus 40 (sv40), 40 newborn taiwan monkeys were inoculated with ad12, ad12, plus sv40, ad12 supplemented with ad12-induced hamster tumor tissue (ad12 tumor) or control specimens (hela or african green monkey kidney cell lysate). among them 26 survived including 8 newborn monkeys inoculated with control specimens. the survivors were observed for 4 years but no tumor was produced. t ... | 1975 | 181217 |
| the oncogenic potential of hepatitis b virus rta181t/ surface truncation mutant. | previously, a less prevalent lamivudine-resistant mutant (rta181t) was discovered in taiwanese patients, in which a stop codon in the surface gene concomitantly occurred, leading to impaired secretion of hepatitis b virus (hbv) surface antigen. the rta181t mutant also conferred drug resistance to adefovir. we discovered a 39-year-old patient with advanced hepatocellular carcionoma, who was seropositive for hbv e antigen but seronegative for hbv surface antigen. nucleotide sequence analysis revea ... | 2008 | 19043921 |