| large-scale sequencing of human influenza reveals the dynamic nature of viral genome evolution. | influenza viruses are remarkably adept at surviving in the human population over a long timescale. the human influenza a virus continues to thrive even among populations with widespread access to vaccines, and continues to be a major cause of morbidity and mortality. the virus mutates from year to year, making the existing vaccines ineffective on a regular basis, and requiring that new strains be chosen for a new vaccine. less-frequent major changes, known as antigenic shift, create new strains ... | 2005 | 16208317 |