| transmission of a multidrug-resistant mycobacterium tuberculosis strain resembling "strain w" among noninstitutionalized, human immunodeficiency virus-seronegative patients. | since 1990, several outbreaks of multidrug-resistant tuberculosis (mdr-tb) have been described among institutionalized patients infected with human immunodeficiency virus (hiv). we describe a community mdr-tb outbreak among hiv-seronegative patients in cape town, south africa. isolates were characterized by restriction fragment length polymorphism (rflp) analysis and dot-blot hybridization analysis of mutations conferring resistance for isoniazid, rifampin, streptomycin, and ethambutol. all isol ... | 1999 | 10515823 |
| high level of discordant igra results in hiv-infected adults and children. | tygerberg district, western cape province, south africa. | 2008 | 18371268 |
| the changing natural history of tuberculosis and hiv coinfection in an urban area of hyperendemicity. | tuberculosis (tb) has proven to be difficult to control in regions with a high prevalence of human immunodeficiency virus (hiv) infection. we previously described high prevalence of hiv infection among adults (23%) and rapidly escalating tb notification rates in a peri-urban township, site-m in cape town, south africa. the combination of delineated boundaries, a well-characterized population, centralized tb record keeping, and high levels of hiv testing make this population uniquely suited for t ... | 2010 | 20397950 |