Publications

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impact of the change from an injectable to a fully oral regimen on patient adherence to ambulatory tuberculosis treatment in dar es salaam, tanzania.to measure the impact on patient adherence to directly observed ambulatory tuberculosis treatment substituting an all-oral treatment regimen for a regimen containing streptomycin.19957579308
enteric viruses associated with hiv infection in tanzanian children with chronic diarrhea.to determine whether specific viruses are associated with hiv infection in tanzanian children with chronic diarrhea.199411361370
extrapulmonary tuberculosis--a simple diagnosis? a retrospective study at dar es salaam, tanzania.data from the national tuberculosis programme show that extrapulmonary tuberculosis is increasing rapidly in tanzania, most likely caused by the human immunodeficiency virus (hiv) epidemic. retrospective data from 271 patients admitted to muhimbili medical centre (mmc), dar es salaam between january 1, 1987 and december 31, 1988 with the diagnosis of extrapulmonary tuberculosis reveal that in only 18% of the cases a bacteriological or histological confirmation of the diagnosis had been made. thi ...19911812603
clinical features of hiv-seropositive and hiv-seronegative patients with tuberculous pleural effusion in dar es salaam, tanzania.in a prospective study, we investigated whether human immunodeficiency virus (hiv) infection alters the clinical presentation in patients with tuberculous pleuritis. one hundred twelve of 118 patients who presented with pleural effusion suffered from tuberculosis (tb); 65 patients (58%) were hiv seropositive. evidence of disseminated tb was found more often in hiv-positive than in hiv-negative patients (30.8% vs 10.6%, p < 0.02). dyspnea, fever, night sweat, fatigue, and diarrhea, severe tachypn ...19947956405
radiographic abnormalities in tuberculosis and risk of coexisting human immunodeficiency virus infection. results from dar-es-salaam, tanzania, and scoring system.first, we evaluated the age profile and chest radiographic abnormalities in 146 patients from dar-es-salaam, tanzania, with new-onset intrathoracic tuberculosis (pulmonary, pleural, or hilar/mediastinal adenopathy), to identify features that were associated with human immunodeficiency virus (hiv) seropositivity or seronegativity; then, we combined these data with those from a companion investigation in burundi to develop a simple scoring system to predict hiv serologic status. using agreed-upon ...19957633743
prevalence of antibodies to human t-lymphotropic virus type 1 (htlv-1) in an hiv-endemic region of africa.serum samples from 267 healthy subjects and patients either infected or not infected with hiv-1 in dar es salaam, tanzania, were examined by enzyme-linked immunosorbent assay and western blot techniques for evidence of htlv-1 infection. specific antibodies were detected in only 1% of the sera. positive sera were likely to be from individuals infected with hiv-1. tanzania and probably the other east african countries are non-endemic for htlv-1. prevalences are too low to provide justification for ...19902226224
a trial of the effect of micronutrient supplementation on treatment outcome, t cell counts, morbidity, and mortality in adults with pulmonary tuberculosis.tuberculosis (tb) often coincides with nutritional deficiencies. the effects of micronutrient supplementation on tb treatment outcomes, clinical complications, and mortality are uncertain.200818471061
a randomized trial of multivitamin supplements and hiv disease progression and mortality.results from observational studies suggest that micronutrient status is a determinant of the progression of human immunodeficiency virus (hiv) disease.200415229304
response to podophyllotoxin treatment of genital warts in relation to hiv-1 infection among patients in dar es salaam, tanzania.forty-two tanzanian patients with genital warts were treated with 0.5% podophyllotoxin solution (wartec) for 3 days. thirteen patients (30.9%) were cured and a further 7 patients (16.7%) had more than 50% of lesions cleared at 6 weeks, while 19 patients were resistant to treatment. three patients had a recurrence of lesions after an initial response. thirty-three patients were tested for serological evidence of infection with human immunodeficiency virus (hiv) and 15 (45.5%) patients were shown ...19957779923
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