| viral dna contamination is responsible for epstein-barr virus detection in cytotoxic t lymphocytes stimulated in vitro with epstein-barr virus b-lymphoblastoid cell line. | epstein-barr virus (ebv)-transformed b-lymphoblastoid cell lines (lcls) are used to prepare human ebv-specific t lymphocytes (ebv-ctl) in vitro. within an lcl, up to 5-7% the cells release infectious ebv, and this has fostered safety concerns for therapeutic applications because of the exposure of t cells to ebv. the release of infectious viruses can be prevented by ganciclovir, but this drug may seriously affect lcl growth. in the wake of these concerns, the present work was designed to compile ... | 2010 | 20809356 |