| scrapie: a clinical assessment. | | 1992 | 1604786 |
| maternal and lateral transmission of scrapie in sheep. | | 1974 | 4212154 |
| prevalence of vacuolar lesions consistent with scrapie in the brains of healthy cull sheep of the shetland islands. | to determine the levels of background scrapie-like pathology in the brains of clinically normal adult sheep, the brains of 1106 sheep from 28 known scrapie-infected flocks and nine apparently uninfected flocks were examined during 1998 and 1999. one per cent of the brains had vacuolar pathology and disease-specific accumulations of prion protein consistent with a diagnosis of scrapie. all the positive animals had at least one allele of the prion protein gene encoding valine at codon 136, and ori ... | 2000 | 11079439 |
| descriptive spatial analysis of scrapie-affected flocks in great britain between january 1993 and december 2002. | the spatial distribution of sheep flocks in great britain with confirmed clinical scrapie between january 1993 and december 2002 inclusive was investigated by using kernel density estimation and a cluster scan test statistic. six statistically significant clusters were identified: three were lower risk, and were centred on the north-western coast of scotland, the north-western coast of wales and the south yorkshire/pennine region; three were of higher risk, and were centred in the central south, ... | 2006 | 16891423 |