| identification of enap-1, an antimicrobial peptide from equine neutrophils. | endogenous, cysteine-rich antimicrobial peptides known as defensins are prominent components of human, rabbit, and rat neutrophils, yet little is known about their occurrence in other mammalian species. although we did not detect mature (i.e., processed) defensins in equine neutrophil granules, we found that these granules contained small amounts of other cysteine-rich peptides with antimicrobial activity. one of these, enap-1, was purified by a combination of gel permeation and reversed-phase h ... | 1992 | 1639474 |
| a comparison of the pulmonary defenses against streptococcal infection in rats and mice following o3 exposure: differences in disease susceptibility and neutrophil recruitment. | ozone (o3) exposure reduces alveolar macrophage (am) phagocytosis in mice and increases their susceptibility to streptococcus zooepidemicus. o3 exposure also decreases am phagocytosis in rats but does not result in mortality to infection. to investigate the mechanism of disease protection in rats, antibacterial defenses of two strains of mice and f344 rats were compared. o3 exposure (3 hr, 0.4 or 0.8 ppm) and infection with s. zooepidemicus resulted in a dose-dependent proliferation of bacteria ... | 1993 | 8248928 |
| bacteremia due to streptococcus zooepidemicus associated with an abdominal aortic aneurysm. | group c streptococci are a common cause of infection in animals but a rare cause of infection in man. to our knowledge, the english literature contains only three cases of arteriosclerotic aneurysms of the abdominal aorta (aaa) secondarily infected with group c beta-hemolytic streptococci. two cases did not survive in spite of adequate antibiotic therapy. one patient responded to aortic repair with a bifurcated woven dacron graft followed by four weeks of high-dose intravenous penicillin. this a ... | 1998 | 9581510 |
| septicemia and meningitis due to streptococcus zooepidemicus. | a case of septicemia and meningitis due to streptococcus zooepidemicus in an immunocompetent patient is reported. this organism is an uncommon human pathogen that sometimes causes severe infection, usually in immunocompromised patients. in the reported case, the patient required to be mechanically ventilated for one week and was treated with intravenous ampicillin and gentamicin. he recovered and was discharged from hospital three weeks after the initial presentation. streptococcus zooepidemicus ... | 1998 | 9707316 |
| meningitis due to group c streptococcus: a case report and review of the literature. | group c streptococci (gcs) are common causes of veterinary diseases and may colonize humans. human diseases due to gcs are uncommon and generally occur in the elderly and persons exposed to animals or animal products. we report a case of streptococcus equi subsp. zooepidemicus meningitis in a horse trainer and review 36 cases of gcs meningitis reported in the literature. the median age was 48 y and the majority of patients were previously healthy. thirty-one percent (11/36) of the reported cases ... | 2010 | 20632899 |
| evaluation of lhp-« (1% hydrogen peroxide) cream versus petrolatum and untreated controls in open wounds in healthy horses: a randomized, blinded control study. | abstract: | 2011 | 21718487 |