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proteomic analysis of the urine of dirofilaria immitis infected dogs.canine cardiopulmonary dirofilariosis caused by dirofilaria immitis habitually develops as a chronic disease affecting pulmonary arteries, lung parenchyma and heart. other organs like kidneys can also be involved. renal pathology is a consequence of glomerulonephritis whose main sign is proteinuria. the aim of the present work is to identify proteins excreted in the urine of d. immitis infected dogs showing proteinuria, and the possible contribution of their loss to heartworm disease. proteinuri ...201424566125
detection of human filarial parasite brugia malayi in dogs by histochemical staining and molecular techniques.human filariasis caused by brugia malayi is still a public health problem in many countries of asia including india, indonesia, malaysia and thailand. the world health organization (who) has targeted to eliminate filariasis by the year 2020 by mass annual single dose diethylcarbamazine administration (mda). results of the mda programme after the first phase was less satisfactory than expected. malayan filariasis caused by b. malayi is endemic in the south of thailand where domestic cat serves as ...201121620569
transcriptomes and pathways associated with infectivity, survival and immunogenicity in brugia malayi l3.filarial nematode parasites cause serious diseases such as elephantiasis and river blindness in humans, and heartworm infections in dogs. third stage filarial larvae (l3) are a critical stage in the life cycle of filarial parasites, because this is the stage that is transmitted by arthropod vectors to initiate infections in mammals. improved understanding of molecular mechanisms associated with this transition may provide important leads for development of new therapies and vaccines to prevent f ...200919527522
eye lesion caused by adult brugia malayi: a first case reported in a child from malaysia.we are reporting a case of an eye lesion caused by an adult brugia malayi. the patient was a 3-year-old chinese boy from kemaman district, terengganu, peninsular malaysia. he presented with a one week history of redness and palpebral swelling of his right eye. he claimed that he could see a worm in his right eye beneath the conjunctiva. he had no history of traveling overseas and the family kept dogs at home. he was referred from kemaman hospital to the eye clinic of hospital tengku ampuan afzan ...200617121289
detection of circulating antigens and parasite specific antibodies in filariasis.in peninsular malaysia, only wuchereria bancrofti and brugia malayi are reported to cause human filariasis. brugia pahangi infects many of the same animal hosts as the zoonotically transmitted subperiodic b. malayi. there is a well-recognized need for improved diagnostic techniques for lymphatic filariasis. parasite antigen detection is a promising new approach, and it will probably prove to be more sensitive and specific than clinical, microscopic and antibody-based serological methods. we rece ...19937973943
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