| in vitro and in vivo activities of haplophyllum myrtifolium against leishmania tropica. | this study aimed to evaluate the in vitro and in vivo leishmanicidal activity of an endemic turkish plant and compare its efficacy with a reference drug. in addition to the in vitro activities of the ethanol, acidified and alkaloid extracts and furoquinoline alkaloids skimmianine and gamma-fagarine, in vivo antileishmanial activitiy of the acidified extract of haplophyllum myrtifolium boiss. (rutaceae) were investigated against leishmania tropica (l. tropica), a causative agent of cutaneous leis ... | 2007 | 18080680 |
| detection of leishmania major and leishmania tropica in domestic cats in the ege region of turkey. | leishmaniosis is a group of diseases caused by different species of leishmania parasites in mammalian species. the aim of the present study was to investigate the presence of leishmania spp. dna in cats using real time polymerase chain reaction (rt-pcr) assays targeting internal transcribed spacer (its1) and heat-shock protein 70 gene (hsp70) regions with leishmania species-specific primers and probes. blood samples were collected from 147 cats (73 female; 74 male) in the endemic regions for zoo ... | 2015 | 26277567 |
| comparison of clinical samples and methods in chronic cutaneous leishmaniasis. | this study aimed at finding out the most effective clinical samples and methods in chronic cutaneous leishmaniasis (ccl). smear, aspiration fluid, and filter paper samples were taken from 104 skin lesions of suspected cases with ccl, and they were compared using microscopic examination, culture, and molecular methods. we characterized four different forms of ccl and identified the causative agents in ccl forms using high-resolution melting curve real-time polymerase chain reaction assay. we obse ... | 2014 | 25223940 |
| the emergence of leishmania major and leishmania donovani in southern turkey. | in southern turkey, leishmania tropica and l. infantum are both the causative agents of cutaneous leishmaniasis (cl) and visceral leishmaniasis (vl), respectively. however, l. major and l. donovani were known to exist after the influx of syrian refugees. | 2014 | 24449479 |
| cutaneous leishmaniasis infection in balb/c mice using a leishmania tropica strain isolated from turkey. | leishmania tropica, which is endemic in turkey, is the causative agent of cutaneous leishmaniasis. leishmania tropica promastigotes (2 x 10(7)) isolated from a patient with dermal leishmaniasis and reproduced in nnn medium were inoculated subcutaneously into the footpads of 10 balb/c mice. cutaneous leishmaniasis developed on the footpads of 4 mice approximately 45 days later. leishmania tropica amastigotes were observed in smear slides and then cultivated in nnn medium. balb/c mice are a suitab ... | 2001 | 11695390 |
| clinical manifestations and genetic variation of leishmania infantum and leishmania tropica in southern turkey. | l. infantum was isolated from cutaneous leishmaniasis (cl) skin lesions in patients having no signs and symptoms of visceral leishmaniasis (vl). similarly, l. tropica had previously been isolated from patients with vl in the absence of cutaneous lesions. it was not certain how visceralization occurred. smears (207) and bone marrow samples (135) were taken from cl and vl-suspected patients, respectively. microscopic examination, its1-pcr, rflp and dna sequencing for all samples were analyzed. the ... | 2015 | 25913665 |