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case-control study of factors associated with human t-cell leukemia virus type i infection in southern miyazaki, japan.an unusual age- and sex-specific distribution and a remarkably restricted geographic seroprevalence characterize human t-cell leukemia virus type i (htlv-i) infection. although the transmission routes of htlv-i are known, these seroepidemiologic features cannot be fully explained.19921593654
high htlv-i proviral dna level associated with abnormal lymphocytes in peripheral blood from asymptomatic carriers.the level of proviral dna in peripheral blood mononuclear cells from a representative group of asymptomatic htlv-i carriers in miyazaki district, an htlv-i endemic area in japan, was determined by a single-cycle polymerase chain reaction method (pcr). of 217 subjects, 26% had a high level of proviral dna, 43% a medium level, 18% a low level, and 13% an undetectable level. in the high-dna group, 60% had at least 0.6% abnormal lymphocytes on peripheral blood smears, significantly higher than in th ...19921601522
uveitis associated with human t-cell lymphotropic virus type i.seroepidemiologic, clinical, and virologic studies were performed to determine whether human t-cell lymphotropic virus type i was closely associated with uveitis in two hospitals. one hospital was in an endemic area of the virus (miyakonojo, miyazaki) and the other hospital was in a less endemic area (kurume). in the endemic area, the seroprevalence of the virus in patients with uveitis without defined causes (35.4%, 62 of 175 patients) was significantly higher than that in patients with nonuvei ...19921642286
[uveitis in human t-lymphotropic virus type i (htlv-i) carriers--1. a seroepidemiological study].a seroepidemiological study was carried out to find out if human t-lymphotropic virus type i (htlv-i) was closely associated with uveitis in two hospitals: one in an area where htlv-i was highly prevalent (miyakonojo, miyazaki) and the other in an area where htlv-i was less prevalent (kurume). in the highly prevalent htlv-i area, the seroprevalence in patients with idiopathic uveitis (78/206, 37.9%) was significantly higher than in patients with non-uveitic ocular diseases (73/380, 19. 2%) or in ...19938328341
heterosexual transmission of human t cell leukemia/lymphoma virus type i among married couples in southwestern japan: an initial report from the miyazaki cohort study.to identify factors that may modify the heterosexual transmission of human t cell leukemia/lymphoma virus type i (htlv-i), 534 married couples enrolled in the miyazaki cohort study between november 1984 and april 1989 were studied: 95 husband htlv-i-seropositive (h+)/wife seropositive (w+), 33 h+/w-, 64 h-/w+, and 342 h-/w-. after 5 years of follow-up, seven seroconversions occurred and clustered significantly among serodiscordant pairs (relative risk [rr] = 41.2); the rate of transmission was 3 ...19938418183
serologic assessment of type 1 and type 2 immunity in healthy japanese adults.we assessed the informativeness of several serologic biomarkers of immune function using serum specimens collected in the miyazaki cohort study from subjects who were seronegative for anti-human t-cell lymphotrophic virus i and anti-hepatitis c virus. to broadly characterize type 1 immune status, we measured ebv antibody titers, because titer profiles associated with cellular immune suppression are well described. we also tested for three type 2 biomarkers: total serum ige, soluble cd23, and sol ...200415298962
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