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interfamilial and intrafamilial genomic diversity and molecular phylogeny of human t-cell lymphotropic virus type i from papua new guinea and the solomon islands.to determine the interstrain genomic diversity and molecular phylogeny of the recently identified variants of human t-cell lymphotropic virus type i (htlv-i) in melanesia, we enzymatically amplified, then directly sequenced representative regions of the gag, pol, and env genes of htlv-i strains from 10 members of four families, including one family from papua new guinea and three families from the solomon islands. when aligned and compared to a japanese strain of htlv-i (atk), the melanesian htl ...19938372432
genetic and phylogenetic analyses of human t-cell lymphotropic virus type i variants from melanesians with and without spastic myelopathy.molecular variants of human t-cell lymphotropic virus type i (htlv-i) have been isolated recently from lifelong residents of remote melanesian populations, including a solomon islander with tropical spastic paraparesis/htlv-i-associated myelopathy (tsp/ham) or htlv-i myeloneuropathy. to clarify the genetic heterogeneity and molecular epidemiology of disease-associated strains of htlv-i, we enzymatically amplified, then directly sequenced representative regions of the gag, pol, env, and px genes ...19947999313
antibodies to htlv-i in populations of the southwestern pacific.sera collected from 1,102 individuals in 14 populations of the southwestern pacific between 1956 and 1979 were tested by elisa for antibodies to human t-cell leukemia virus type i (htlv-i). selected sera were also tested by particle agglutination and immunoblotting. six of the populations had prevalences of antibodies greater than 4%, two populations had prevalences greater than 15%. six populations had antibody prevalences of 2% or less. three populations from the coast and northern islands of ...19883209991
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