| molecular characterization and immunogenicity of neutralization-sensitive babesia bigemina merozoite surface proteins. | monoclonal antibodies binding to the surface of live mexico isolate babesia bigemina merozoites have defined 4 parasite-encoded surface antigens (36, 45, 55, and 58 kda) that are potential targets for immune-mediated neutralization of merozoites. in this study, we have characterized the post-translational modification, antigenic polymorphism, and immunogenicity of these 4 proteins. monoclonal antibody immunoaffinity-purified 36- and 55-kda polypeptides were identical in gel electrophoresis to im ... | 1991 | 1944418 |
| monoclonal antibody to a conserved epitope on proteins encoded by babesia bigemina and present on the surface of intact infected erythrocytes. | to define babesia bigemina-specific antigens on the surface of infected erythrocytes, monoclonal antibodies (mabs) were identified by live-cell immunofluorescence. as determined by live-cell immunofluorescence, two mabs made to the mexico strain reacted with the mexico strain and three kenya strains, while three mabs made to the kenya-ngong strain reacted with the kenya strains but not the mexico strain. binding of mab 44.18 (made to the mexico strain) to a strain-common epitope was confirmed by ... | 1995 | 7543884 |